| Gene Symbol |
PRTN3
|
| Entrez Gene |
5657
|
| Alt Symbol |
ACPA, AGP7, C-ANCA, CANCA, MBN, MBT, NP-4, NP4, P29, PR-3, PR3
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
proteinase 3
|
| Other Description |
C-ANCA antigen|Wegener granulomatosis autoantigen|azurophil granule protein 7|leukocyte proteinase 3|myeloblastin|neutrophil proteinase 4|serine proteinase, neutrophil|wegener autoantigen
|
| Swissprots |
P15637 Q9UQD8 Q6LBN2 Q4VB08 Q4VB09 P18078 P24158 Q6LBM7 Q9UD25
|
| Accessions |
AAB59364 EAW69590 EAW69591 P24158 BC096183 AAH96183 BC096184 AAH96184 BC096185 AAH96185 BC096186 AAH96186 FN647680 CBI83574 M29142 AAA36342 M75154 AAA59558 X55668 CAA39203 X56132 CAA39597 X56606 CAA39943 XM_011528136 XP_011526438 XM_011546889 XP_011545191 NM_002777 NP_002768
|
| Function |
Polymorphonuclear leukocyte serine protease that degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro) and causes emphysema when administered by tracheal insufflation to hamsters.
|
