PRTN3

Gene Symbol PRTN3
Entrez Gene 5657
Alt Symbol ACPA, AGP7, C-ANCA, CANCA, MBN, MBT, NP-4, NP4, P29, PR-3, PR3
Species Human
Gene Type protein-coding
Description proteinase 3
Other Description C-ANCA antigen|Wegener granulomatosis autoantigen|azurophil granule protein 7|leukocyte proteinase 3|myeloblastin|neutrophil proteinase 4|serine proteinase, neutrophil|wegener autoantigen
Swissprots P15637 Q9UQD8 Q6LBN2 Q4VB08 Q4VB09 P18078 P24158 Q6LBM7 Q9UD25
Accessions AAB59364 EAW69590 EAW69591 P24158 BC096183 AAH96183 BC096184 AAH96184 BC096185 AAH96185 BC096186 AAH96186 FN647680 CBI83574 M29142 AAA36342 M75154 AAA59558 X55668 CAA39203 X56132 CAA39597 X56606 CAA39943 XM_011528136 XP_011526438 XM_011546889 XP_011545191 NM_002777 NP_002768
Function Polymorphonuclear leukocyte serine protease that degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro) and causes emphysema when administered by tracheal insufflation to hamsters.

PR3 (D-1) - sc-74534 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
PR3 (D-1): sc-74534. Western blot analysis of PR3 expression in HL-60 (A), RAW 264.7 (B) and KNRK (C) whole cell lysates.

PR3 (C-17) - sc-19746 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

PR3 (H-60) - sc-28818 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
PR3 (H-60): sc-28818. Western blot analysis of PR3 expression in HL-60 whole cell lysate.

Anti-PR3 antibody - ab202968 from Abcam

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of formalin-fixed, paraffin-embedded Rat brain labeling PR3 with ab202968 at 1/200 dilution followed by conjugation to the secondary antibody and DAB staining.

Anti-PR3 antibody - ab21592 from Abcam

Prices $372.00
Sizes 250 µl
Host Rabbit
Clonality Polyclonal

Anti-PR3 antibody - ab103632 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-PR3 antibody (ab103632) at 5 µg/ml + Mouse brain tissue lysate at 50 µg

Anti-PR3 antibody - ab191282 from Abcam

Prices $376.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Anti-PR3 antibody (ab191282) at 2 µg/ml + Human Spleen lysate in RIPA buffer at 35 µg

Anti-PR3 antibody - ab88097 from Abcam

Prices $376.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Anti-PR3 antibody (ab88097) at 1 µg/ml + hman spleen tissue lysate at 50 µg

Anti-PR3 antibody - ab85897 from Abcam

Host Sheep
Clonality Polyclonal

Anti-PR3 antibody [1B10] - ab10197 from Abcam

Prices $372.00
Sizes 250 µg
Host Mouse
Clonality Monoclonal
Clone 1B10

Anti-PR3 antibody [1F10] - ab10198 from Abcam

Prices $359.00
Sizes 250 µg
Host Mouse
Clonality Monoclonal
Clone 1F10

Anti-PR3 antibody [2E1] - ab10200 from Abcam

Prices $359.00
Sizes 250 µg
Host Mouse
Clonality Monoclonal
Clone 2E1

Anti-PR3 antibody [EPR6277] - ab133613 from Abcam

Prices $385.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR6277
All lanes : Anti-PR3 antibody [EPR6277] (ab133613) at 1/1000 dilutionLane 1 : HL60 lysates Lane 2 : Human spleen lysates Lysates/proteins at 10 µg per lane.SecondaryHRP labelled goat anti-rabbit at 1/2000 dilution

Anti-PR3 antibody [MCPR3-2] - ab80705 from Abcam

Prices $379.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone MCPR3-2
Overlay histogram showing THP1 cells stained with ab80705 (red line). The cells were fixed with 4% paraformaldehyde (10 min) and then permeabilized with 0.1% PBS-Tween for 20 min. The cells were then incubated in 1x PBS / 10% human serum / 0.3M glycine to block non-specific protein-protein interactions followed by the antibody (ab80705, 0.1μg/1x106 cells) for 30 min at 22°C. The secondary antibody used was Alexa Fluor® 488 goat anti-mouse IgG (H&L) (ab150113) at 1/2000 dilution for 30 min at 22°C. Isotype control antibody (black line) was mouse IgG1 [ICIGG1] (ab91353, 1μg/1x106 cells) used under the same conditions. Unlabelled sample (blue line) was also used as a control. Acquisition of >5,000 events were collected using a 20mW Argon ion laser (488nm) and 525/30 bandpass filter. This antibody gave a positive signal in THP1 cells fixed with 80% methanol (5 min)/permeabilized with 0.1% PBS-Tween for 20 min used under the same conditions.

Anti-PR3 antibody [PR3G-2] (FITC) - ab65255 from Abcam

Prices $378.00
Sizes 500 µl
Host Mouse
Clonality Monoclonal
Clone PR3G-2
Overlay histogram showing THP1 cells stained with ab65255 (red line). The cells were fixed with 80% methanol (5 min) and then permeabilized with 0.1% PBS-Tween for 20 min. The cells were then incubated in 1x PBS / 10% normal goat serum / 0.3M glycine to block non-specific protein-protein interactions followed by the antibody (ab65255, 0.5µg/1x106 cells) for 30 min at 22ºC. Isotype control antibody (black line) was mouse IgG1 [MOPC-21] (FITC) (ab18435, 0.5µg/1x106 cells) used under the same conditions. Unlabelled sample (blue line). Acquisition of >5,000 events were collected using a 20mW Argon ion laser (488nm) and 525/30 bandpass filter.

Anti-PR3 antibody [WGM2] - ab91181 from Abcam

Prices $378.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone WGM2

Anti-PR3 antibody [WGM2] (FITC) - ab91182 from Abcam

Prices $378.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone WGM2
Overlay histogram showing peripheral blood lymphocytes cells stained with ab91182 (red line). The cells were fixed with 4% paraformaldehydel (10 min) and then permeabilized with 0.1% PBS-Tween for 20 min. The cells were then incubated in 1x PBS / 10% normal goat serum / 0.3M glycine to block non-specific protein-protein interactions followed by the antibody (ab91182, 0.5µg/1x106 cells) for 30 min at 22ºC. Isotype control antibody (black line) was mouse IgG1 (1µg/1x106 cells ). Acquisition of >5,000 events was performed.

Anti-PRTN3 / Proteinase 3 Antibody - LS-C38484 from LifeSpan Bioscience

Prices $455.00
Sizes 500 µg
Host Mouse
Clonality Monoclonal

Anti-PRTN3 / Proteinase 3 Antibody - LS-C38480 from LifeSpan Bioscience

Prices $335.00
Sizes 2 ml
Host Human
Clonality Polyclonal

Anti-PRTN3 / Proteinase 3 Antibody - LS-C84727 from LifeSpan Bioscience

Prices $515.00
Sizes 1 mg
Host Mouse
Clonality Monoclonal

Anti-PRTN3 / Proteinase 3 Antibody - LS-C86228 from LifeSpan Bioscience

Prices $475.00
Sizes 250 µl
Host Rabbit
Clonality Polyclonal

Anti-PRTN3 / Proteinase 3 Antibody - LS-C84728 from LifeSpan Bioscience

Prices $495.00
Sizes 1 mg
Host Mouse
Clonality Monoclonal

Anti-PRTN3 / Proteinase 3 Antibody - LS-C38485 from LifeSpan Bioscience

Prices $435.00
Sizes 500 µg
Host Mouse
Clonality Monoclonal

Anti-PRTN3 / Proteinase 3 Antibody (clone MCPR3-2, Azide-free) - LS-C87702 from LifeSpan Bioscience

Prices $610.00, $1,015.00
Sizes 100 µg, 200 µg
Host Mouse
Clonality Monoclonal
Clone MCPR3-2

Anti-PRTN3 / Proteinase 3 Antibody (clone MCPR3-2) - LS-C87701 from LifeSpan Bioscience

Prices $295.00, $555.00, $925.00
Sizes 100 µl, 100 µg, 200 µg
Host Mouse
Clonality Monoclonal
Clone MCPR3-2
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