Gene Symbol | HEXA |
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Entrez Gene | 3073 |
Alt Symbol | TSD |
Species | Human |
Gene Type | protein-coding |
Description | hexosaminidase A (alpha polypeptide) |
Other Description | N-acetyl-beta-glucosaminidase subunit alpha|beta-N-acetylhexosaminidase subunit alpha|beta-hexosaminidase subunit alpha|hexosaminidase subunit A |
Swissprots | Q6AI32 B4DKE7 Q53HS8 E7ENH7 P06865 |
Accessions | AAB00965 AAD13932 AER36552 BAL04456 BAL04457 BAL04458 BAL04459 BAL04460 BAL04461 BAL04462 BAL04463 EAW77902 P06865 AK222502 BAD96222 AK296528 BAG59159 AK297678 BAG60039 AK301000 BAG62619 AK301138 BAG62730 AK307770 AK310154 BC001138 AAH01138 BC018927 AAH18927 BC021030 AAH21030 BC034424 BC084537 AAH84537 BP356349 BX537989 CR627386 CAH10482 DC356933 DQ892696 ABM83622 EU176728 ABW03529 J04178 M13520 AAA51827 S61298 AAD13927 S76980 AAB33748 S76982 AAD14242 S76984 AAD14243 S77043 AAD14246 NM_000520 NP_000511 |
Function | Responsible for the degradation of GM2 gangliosides, and a variety of other molecules containing terminal N-acetyl hexosamines, in the brain and other tissues. The form B is active against certain oligosaccharides. The form S has no measurable activity. |
Subcellular Location | Lysosome. |
Top Pathways | Lysosome, Amino sugar and nucleotide sugar metabolism, Glycosphingolipid biosynthesis - globo series, Other glycan degradation, Glycosaminoglycan degradation |
Human HEXA full length protein - ab116804 from Abcam
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Human HEXA full length protein - ab140049 from Abcam
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Human HEXA full length protein - ab198482 from Abcam
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Human HEXA full length protein - ab201898 from Abcam
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HEXA Antibody Blocking Peptide - LS-E22335 from LifeSpan Bioscience
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HEXA Antibody Blocking Peptide - LS-E8567 from LifeSpan Bioscience
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HEXA Antibody Blocking Peptide - LS-E8566 from LifeSpan Bioscience
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Hexosaminidase A/HEXA Recombinant Protein - H00003073-P01 from Novus Biologicals
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Recombinant Human Hexosaminidase A/HEXA Protein - NBP2-23121 from Novus Biologicals
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HEXA-Antibody-Center-Blocking-Peptide - BP6942c from Abgent, a WuXi AppTec company
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HEXA-Antibody-N-term-Blocking-Peptide - BP6942a from Abgent, a WuXi AppTec company
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Recombinant Human Hexosaminidase A/HEXA, CF - 6237-GH-020 from R&D Systems
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Human HEXA His tag protein - orb84592 from Biorbyt
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HEXA Blocking Peptide - 33R-9958 from Fitzgerald
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HEXA protein - 80R-4251 from Fitzgerald
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HEXA protein (His tag) - 80R-2645 from Fitzgerald
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Beta-hexosaminidase alpha / HEXA (89-529, His-tag) - AR50765PU-N from Acris Antibodies
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Beta-hexosaminidase alpha / HEXA (89-529, His-tag) - AR50765PU-S from Acris Antibodies
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Beta-hexosaminidase alpha / HEXA (23-529, His-tag) - AR51933PU-N from Acris Antibodies
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Beta-hexosaminidase alpha / HEXA (23-529, His-tag) - AR51933PU-S from Acris Antibodies
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Beta-hexosaminidase alpha / HEXA - H00003073-P01-10 from Acris Antibodies
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Beta-hexosaminidase alpha / HEXA - H00003073-P01-25 from Acris Antibodies
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HEXA, 89-529aa Human, His tag, E.coli - 01-P1941 from ARP American Research Products
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HEXA fusion protein - ag1854 from Proteintech Group
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Hexa-His - GWB-E66480 from Genway Biotech
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