Gene Symbol | Wnt3a |
---|---|
Entrez Gene | 22416 |
Alt Symbol | Wnt-3a, vt |
Species | Mouse |
Gene Type | protein-coding |
Description | wingless-type MMTV integration site family, member 3A |
Other Description | protein Wnt-3a|vestigial tail|wingless-related MMTV integration site 3A |
Swissprots | P27467 |
Accessions | CAI38662 EDL07662 P27467 AV026498 BC152754 AAI52755 X56842 CAA40173 NM_009522 NP_033548 |
Function | Ligand for members of the frizzled family of seven transmembrane receptors. Wnt-3 and Wnt-3a play distinct roles in cell-cell signaling during morphogenesis of the developing neural tube. |
Subcellular Location | Secreted, extracellular space, extracellular matrix. |
Tissue Specificity | Dorsal portion of the neural tube (developing roof plate), and mesenchyme tissue surrounding the umbilical veins. |
Top Pathways | HTLV-I infection, Proteoglycans in cancer, Signaling pathways regulating pluripotency of stem cells, MicroRNAs in cancer, Hippo signaling pathway |