| Gene Symbol |
SPCS1
|
| Entrez Gene |
28972
|
| Alt Symbol |
HSPC033, SPC1, SPC12, YJR010C-A
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
signal peptidase complex subunit 1 homolog (S. cerevisiae)
|
| Other Description |
SPase 12 kDa subunit|microsomal signal peptidase 12 kDa subunit|signal peptidase 12kDa|signal peptidase complex subunit 1
|
| Swissprots |
Q9Y6A9 Q9BVW1 B3KNF8
|
| Accessions |
EAW65257 Q9Y6A9 AF092138 AAD40380 AK027426 BAG51320 AX775783 CAE11591 AX775785 CAE11592 AX775787 CAE11593 AX775833 CAE11616 BC000884 AAH00884 BG724036 BI826431 BQ423345 BU070128 CA309210 DB459917 L38852 AAL31361 NM_014041 NP_054760
|
| Function |
Component of the microsomal signal peptidase complex which removes signal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum. {ECO:0000250}.
|
| Subcellular Location |
Microsome membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
|
| Top Pathways |
Protein export
|
![Western Blot: SPCS1 Overexpression Lysate (Adult Normal) [NBL1-16388] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for SPCS1.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/6595_SPCS1%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-16388-img0002.jpg)