| Gene Symbol |
mns1
|
| Entrez Gene |
2541719
|
| Alt Symbol |
SPAPB1E7.13c
|
| Species |
S. pombe
|
| Gene Type |
protein-coding
|
| Description |
mannosyl-oligosaccharide 1,2-alpha-mannosidase
|
| Other Description |
-
|
| Swissprots |
Q9P7C3 Q9C0Z6
|
| Accessions |
CAC36930 Q9P7C3 NM_001019563 NP_594139
|
| Function |
Involved in glycoprotein quality control as it is important for the targeting of misfolded glycoproteins for degradation. It trims a single alpha-1,2-linked mannose residue from Man(9)GlcNAc(2) to produce Man(8)GlcNAc(2) with low efficiency. {ECO:0000269|PubMed:16079177}.
|
| Subcellular Location |
Membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.
|
| Top Pathways |
N-Glycan biosynthesis, Protein processing in endoplasmic reticulum, Various types of N-glycan biosynthesis
|