| Gene Symbol | mns1 |
|---|---|
| Entrez Gene | 2541719 |
| Alt Symbol | SPAPB1E7.13c |
| Species | S. pombe |
| Gene Type | protein-coding |
| Description | mannosyl-oligosaccharide 1,2-alpha-mannosidase |
| Other Description | - |
| Swissprots | Q9P7C3 Q9C0Z6 |
| Accessions | CAC36930 Q9P7C3 NM_001019563 NP_594139 |
| Function | Involved in glycoprotein quality control as it is important for the targeting of misfolded glycoproteins for degradation. It trims a single alpha-1,2-linked mannose residue from Man(9)GlcNAc(2) to produce Man(8)GlcNAc(2) with low efficiency. {ECO:0000269|PubMed:16079177}. |
| Subcellular Location | Membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}. |
| Top Pathways | N-Glycan biosynthesis, Protein processing in endoplasmic reticulum, Various types of N-glycan biosynthesis |