Gene Symbol | TF |
---|---|
Entrez Gene | 7018 |
Alt Symbol | PRO1557, PRO2086, TFQTL1 |
Species | Human |
Gene Type | protein-coding |
Description | transferrin |
Other Description | beta-1 metal-binding globulin|serotransferrin|siderophilin |
Swissprots | Q9NQB8 P02787 O43890 Q9UHV0 Q1HBA5 |
Accessions | AAA61141 AAA61143 AAA61145 AAA61147 AAA61148 AAC63506 AAK77664 AAP45055 ABF47110 CAA28265 CAT02257 CAV33839 CBX51251 CBX51253 EAW79164 EAW79165 EAW79166 EAW79167 EAW79168 EAW79169 EAW79170 P02787 AF118093 AAF22037 AJ252279 CAB96907 AK126941 AK222755 BAD96475 AK293842 BAG57240 AK295334 BAG58308 AK295419 BAG58369 AK303753 BAG64724 AK312094 BAG35030 BC020671 AAH20671 BC022262 BC045772 BC054870 BC059367 AAH59367 BU740589 BX537660 BX648533 CR936810 DC352309 DQ923758 ABI97197 M12525 AAA61142 M12530 AAA61140 M26641 AAA61233 S95936 AAB22049 U88581 AAB97880 XM_011513100 XP_011511402 NM_001063 NP_001054 |
Function | Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Serum transferrin may also have a further role in stimulating cell proliferation. |
Subcellular Location | Secreted. |
Tissue Specificity | Expressed by the liver and secreted in plasma. |
Top Pathways | Mineral absorption |