Gene Symbol | SYT8 |
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Entrez Gene | 90019 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | synaptotagmin VIII |
Other Description | synaptotagmin-8|sytVIII |
Swissprots | A6NFJ4 Q9NSV9 Q8NBV8 |
Accessions | CAF86504 EAX02465 EAX02466 Q8NBV8 AK075202 BAC11467 AK131292 BAD18463 AK293395 BAG56904 AL137708 CAB70885 AY353087 AAQ57209 BC038591 BC144657 BC144659 BC144660 BC144661 BC160127 AAI60127 BP225728 BX365067 BX396540 BX399734 CB321892 CV572958 XM_011520455 XP_011518757 XM_011520456 XP_011518758 XM_011520457 XP_011518759 XM_011520458 XP_011518760 NM_001290332 NP_001277261 NM_001290333 NP_001277262 NM_001290334 NP_001277263 NM_138567 NP_612634 |
Function | Isoform 4 may play a role in the trafficking and exocytosis of secretory vesicles in non-neuronal tissues. Mediates Ca(2+)-regulation of exocytosis acrosomal reaction in sperm. May mediate Ca(2+)-regulation of exocytosis in insulin secreted cells (By similarity). {ECO:0000250}. |
Subcellular Location | Cell membrane {ECO:0000250}; Single-pass type III membrane protein {ECO:0000250}. Cytoplasmic vesicle, secretory vesicle, acrosome {ECO:0000250}. |
Synaptotagmin VIII CRISPR/Cas9 KO Plasmid (h) - sc-413818 from Santa Cruz Biotechnology
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Synaptotagmin VIII HDR Plasmid (h) - sc-413818-HDR from Santa Cruz Biotechnology
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Synaptotagmin VIII Double Nickase Plasmid (h) - sc-413818-NIC from Santa Cruz Biotechnology
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Synaptotagmin VIII Double Nickase Plasmid (h2) - sc-413818-NIC-2 from Santa Cruz Biotechnology
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Synaptotagmin VIII CRISPR Activation Plasmid (h) - sc-413818-ACT from Santa Cruz Biotechnology
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Synaptotagmin VIII CRISPR Activation Plasmid (h2) - sc-413818-ACT-2 from Santa Cruz Biotechnology
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Synaptotagmin VIII Lentiviral Activation Particles (h) - sc-413818-LAC from Santa Cruz Biotechnology
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Synaptotagmin VIII Lentiviral Activation Particles (h2) - sc-413818-LAC-2 from Santa Cruz Biotechnology
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Synaptotagmin VIII siRNA (h) - sc-96830 from Santa Cruz Biotechnology
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Synaptotagmin VIII shRNA Plasmid (h) - sc-96830-SH from Santa Cruz Biotechnology
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Synaptotagmin VIII shRNA (h) Lentiviral Particles - sc-96830-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU097081 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN20928 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20928 from Sigma-Aldrich
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shRNA set against Human SYT8 (NM_138567.3) - SHH422092 from Creative biogene
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shRNA set against Human SYT8(NM_138567.3) - SHL051796 from Creative biogene
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SYT8 miRNA 3'UTR clone - MiUTR1H-10125 from Creative biogene
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