| Gene Symbol |
secA
|
| Entrez Gene |
944821
|
| Alt Symbol |
ECK0099, JW0096, azi, pea, prlD
|
| Species |
Escherichia coli
|
| Gene Type |
protein-coding
|
| Description |
preprotein translocase subunit, ATPase
|
| Other Description |
-
|
| Swissprots |
P75642 P10408
|
| Accessions |
AAC73209 NP_414640
|
| Function |
Required for protein export, interacts with the SecYEG preprotein conducting channel. SecA has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein- SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. {ECO:0000269|PubMed:15140892}.
|
| Subcellular Location |
Cell inner membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Note=Distribution is 50-50.
|
| Top Pathways |
Protein export, Bacterial secretion system
|