Gene Symbol | BRINP3 |
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Entrez Gene | 339479 |
Alt Symbol | DBCCR1L, DBCCR1L1, FAM5C |
Species | Human |
Gene Type | protein-coding |
Description | bone morphogenetic protein/retinoic acid inducible neural-specific 3 |
Other Description | BMP/retinoic acid-inducible neural-specific protein 3|DBCCR1-like protein 1|family with sequence similarity 5, member C|protein FAM5C |
Swissprots | O95726 Q2M330 B3KVP1 Q76B58 B7Z260 |
Accessions | EAW91222 Q76B58 AB111893 BAD04066 AK123024 BAG53853 AK123637 BAG53928 AK294365 BAH11746 BC105052 AAI05053 BC105054 AAI05055 U67037 AAD09521 XM_005245117 XP_005245174 XM_005245118 XP_005245175 XM_005245120 XP_005245177 XM_011509472 XP_011507774 XM_011509473 XP_011507775 XM_011509474 XP_011507776 XM_011509475 XP_011507777 XM_011509476 XP_011507778 NM_199051 NP_950252 |
Function | Inhibits neuronal cell proliferation by negative regulation of the cell cycle transition. Promotes pituitary gonadotrope cell proliferation, migration and invasion, when overexpressed. May play a role in cell pituitary tumor development. {ECO:0000269|PubMed:17138656}. |
Subcellular Location | Secreted {ECO:0000305}. Mitochondrion {ECO:0000250}. |
Tissue Specificity | Strongly expressed in oral keratinocytes compared to the weak expression in tongue squamous cell carcinoma (SCC). Expressed in endothelial and aortic smooth muscle cells. Overexpressed in gonadotropinomas compared to normal pituitarie tissues. {ECO:0000269|PubMed:17138656, ECO:0000269|PubMed:18430236, ECO:0000269|PubMed:19787213}. |
Human FAM5C full length protein - ab166266 from Abcam
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BRINP3 / FAM5C Antibody Blocking Peptide - LS-E10157 from LifeSpan Bioscience
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FAM5C Recombinant Protein - H00339479-P01 from Novus Biologicals
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FAM5C-Antibody-N-term-Blocking-Peptide - BP9487a from Abgent, a WuXi AppTec company
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FAM5C - H00339479-P01 from Acris Antibodies
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FAM5C fusion protein - ag18655 from Proteintech Group
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FAM5C fusion protein - ag18455 from Proteintech Group
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Recombinant Family With Sequence Similarity 5, Member C (FAM5C) - RPR030Hu01 from Uscn Life Science Inc.
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Recombinant Family With Sequence Similarity 5, Member C (FAM5C) - RPR030Hu01 from Cloud-clone
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Recombinant Human Protein FAM5C(FAM5C) - CSB-YP755233HU CSB-EP755233HU CSB-BP755233HU CSB-MP755233HU from Cusabio
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Family With Sequence Similarity 5, Member C Protein (Recombinant) - abx168242 from Abbexa
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FAM5C Peptide, Human - M34GP05458H from Creative Peptides
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FAM5C Recombinant Protein Antigen - NBP2-31581PEP from Novus Biologicals
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Recombinant Family With Sequence Similarity 5, Member C (FAM5C) - RPU53310 from Biomatik
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BRINP3 Recombinant Protein (OPCD03078) - OPCD03078 from Aviva Systems Biology
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Protein FAM5C (FAM5C), Recombinant Protein - MBS1362993 from MyBioSource
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