Gene Symbol | MPV17L |
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Entrez Gene | 255027 |
Alt Symbol | M-LPH, MLPH1, MLPH2, MPV17L1 |
Species | Human |
Gene Type | protein-coding |
Description | MPV17 mitochondrial membrane protein-like |
Other Description | M-LP homolog|Mpv17-like protein type 1|Mpv17-like protein type 2|mpv17-like protein |
Swissprots | Q2QL34 Q8N8E9 B4DDY1 Q6P7T6 |
Accessions | EAW53914 EAW53915 Q2QL34 AK096918 BAC04895 AK293380 BAG56892 BC061514 AAH61514 BM838624 DQ004255 AAY58892 DQ004256 AAY58893 XM_011522445 XP_011520747 XM_011546695 XP_011544997 NM_001128423 NP_001121895 NM_173803 NP_776164 |
Function | Isoform 1 participates in reactive oxygen species metablism by up- or down-regulation of the genes of antioxidant enzymes. {ECO:0000269|PubMed:16631601}. |
Subcellular Location | Isoform 1: Peroxisome membrane; Multi-pass membrane protein. |
Tissue Specificity | Isoform 1 is detected in the kidney (at protein level). Isoform 1 and isoform 2 are expressed in the kidney, heart, liver, lung, pancreas and skeletal muscle. {ECO:0000269|PubMed:16631601}. |
Top Pathways | Peroxisome |
MPV17L CRISPR/Cas9 KO Plasmid (h) - sc-410396 from Santa Cruz Biotechnology
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MPV17L HDR Plasmid (h) - sc-410396-HDR from Santa Cruz Biotechnology
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MPV17L Double Nickase Plasmid (h) - sc-410396-NIC from Santa Cruz Biotechnology
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MPV17L Double Nickase Plasmid (h2) - sc-410396-NIC-2 from Santa Cruz Biotechnology
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MPV17L CRISPR Activation Plasmid (h) - sc-410396-ACT from Santa Cruz Biotechnology
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MPV17L CRISPR Activation Plasmid (h2) - sc-410396-ACT-2 from Santa Cruz Biotechnology
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MPV17L Lentiviral Activation Particles (h) - sc-410396-LAC from Santa Cruz Biotechnology
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MPV17L Lentiviral Activation Particles (h2) - sc-410396-LAC-2 from Santa Cruz Biotechnology
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MPV17L siRNA (h) - sc-93329 from Santa Cruz Biotechnology
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MPV17L shRNA Plasmid (h) - sc-93329-SH from Santa Cruz Biotechnology
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MPV17L shRNA (h) Lentiviral Particles - sc-93329-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU127261 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN14515 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND14515 from Sigma-Aldrich
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MPV17L siRNA (Human) - CRJ6703 from Cohesion Biosciences
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shRNA set against Human Mpv17l (NM_173803.3) - SHH344080 from Creative biogene
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Human MPV17L siRNA - orb277204 from Biorbyt
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MPV17L shRNA Plasmid (Human) - CHJ6703 from Cohesion Biosciences
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MPV17L miRNA 3'UTR clone - MiUTR4H-TG05610 from Creative biogene
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