| Gene Symbol |
Dpm2
|
| Entrez Gene |
29640
|
| Alt Symbol |
-
|
| Species |
Rat
|
| Gene Type |
protein-coding
|
| Description |
dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit
|
| Other Description |
DPM synthase subunit 2|dolichol phosphate-mannose biosynthesis regulatory protein|dolichol-phosphate (beta-D) mannosyltransferase 2|dolichol-phosphate mannose synthase subunit 2|dolichol-phosphate mannosyltransferase 2
|
| Swissprots |
Q9Z325
|
| Accessions |
EDL93229 Q9Z325 AB013359 BAA33972 BC070512 NM_019252 NP_062125
|
| Function |
Regulates the biosynthesis of dolichol phosphate- mannose. Regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex; essential for the ER localization and stable expression of DPM1. When associated with the GPI-GlcNAc transferase (GPI-GnT) complex enhances but is not essential for its activity. {ECO:0000269|PubMed:9724629}.
|
| Subcellular Location |
Endoplasmic reticulum membrane {ECO:0000269|PubMed:9724629}; Multi-pass membrane protein {ECO:0000269|PubMed:9724629}.
|
| Top Pathways |
N-Glycan biosynthesis, Glycosylphosphatidylinositol(GPI)-anchor biosynthesis
|