| Gene Symbol |
BCAT1
|
| Entrez Gene |
586
|
| Alt Symbol |
BCATC, BCT1, ECA39, MECA39, PNAS121, PP18
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
branched chain amino-acid transaminase 1, cytosolic
|
| Other Description |
branched chain aminotransferase 1, cytosolic|branched-chain-amino-acid aminotransferase, cytosolic|placental protein 18
|
| Swissprots |
Q96MY9 Q68DQ7 B3KY27 B7Z5L0 F5H5E4 B7Z2M5 P54687
|
| Accessions |
EAW96497 EAW96498 EAW96499 P54687 AA376058 AF277179 AK024923 AK025615 AK056255 BAB71129 AK128527 BAG54689 AK294879 BAH11911 AK299088 BAH12946 BC026006 BC033864 BM458559 BU618839 BU730066 BX474651 BX647122 CR749308 CAH18163 DC385021 U21551 AAB08528 XM_011520810 XP_011519112 NM_001178091 NP_001171562 NM_001178092 NP_001171563 NM_001178093 NP_001171564 NM_001178094 NP_001171565 NM_005504 NP_005495
|
| Function |
Catalyzes the first reaction in the catabolism of the essential branched chain amino acids leucine, isoleucine, and valine.
|
| Subcellular Location |
Cytoplasm.
|
| Tissue Specificity |
During embryogenesis, expressed in the brain and kidney. Overexpressed in MYC-induced tumors such as Burkitt's lymphoma.
|
| Top Pathways |
Valine, leucine and isoleucine biosynthesis, Biosynthesis of amino acids, 2-Oxocarboxylic acid metabolism, Valine, leucine and isoleucine degradation, Pantothenate and CoA biosynthesis
|