Gene Symbol | LALBA |
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Entrez Gene | 3906 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | lactalbumin, alpha- |
Other Description | alpha-lactalbumin|lactose synthase B protein|lysozyme-like protein 7 |
Swissprots | Q6FGX0 P00709 Q9UDK4 |
Accessions | BAC06860 CAA28799 CAA28800 EAW57990 P00709 BC069103 AAH69103 BC112316 AAI12317 BC112318 AAI12319 BX281629 CR541987 CAG46784 CR542017 CAG46814 HQ258062 ADR82816 J00270 AAA60345 XM_006719395 XP_006719458 XM_011538342 XP_011536644 XM_011538343 XP_011536645 NM_002289 NP_002280 |
Function | Regulatory subunit of lactose synthase, changes the substrate specificity of galactosyltransferase in the mammary gland making glucose a good acceptor substrate for this enzyme. This enables LS to synthesize lactose, the major carbohydrate component of milk. In other tissues, galactosyltransferase transfers galactose onto the N-acetylglucosamine of the oligosaccharide chains in glycoproteins. |
Subcellular Location | Secreted. |
Tissue Specificity | Mammary gland specific. Secreted in milk. |
Top Pathways | Galactose metabolism |
α-lactalbumin CRISPR/Cas9 KO Plasmid (h) - sc-417592 from Santa Cruz Biotechnology
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α-lactalbumin HDR Plasmid (h) - sc-417592-HDR from Santa Cruz Biotechnology
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α-lactalbumin Double Nickase Plasmid (h) - sc-417592-NIC from Santa Cruz Biotechnology
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α-lactalbumin Double Nickase Plasmid (h2) - sc-417592-NIC-2 from Santa Cruz Biotechnology
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α-lactalbumin CRISPR Activation Plasmid (h) - sc-417592-ACT from Santa Cruz Biotechnology
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α-lactalbumin CRISPR Activation Plasmid (h2) - sc-417592-ACT-2 from Santa Cruz Biotechnology
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α-lactalbumin Lentiviral Activation Particles (h) - sc-417592-LAC from Santa Cruz Biotechnology
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α-lactalbumin Lentiviral Activation Particles (h2) - sc-417592-LAC-2 from Santa Cruz Biotechnology
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α-lactalbumin siRNA (h) - sc-72407 from Santa Cruz Biotechnology
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α-lactalbumin shRNA Plasmid (h) - sc-72407-SH from Santa Cruz Biotechnology
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α-lactalbumin shRNA (h) Lentiviral Particles - sc-72407-V from Santa Cruz Biotechnology
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Lactalbumin Alpha RNAi - H00003906-R01 from Novus Biologicals
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CompoZr® Knockout ZFN Kit - CKOZFN11525 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND11525 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR01665 from Sigma-Aldrich
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LALBA siRNA (Human) - CRH2646 from Cohesion Biosciences
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shRNA set against Human LALBA (NM_002289.2) - SHH328187 from Creative biogene
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shRNA set against Human LALBA(NM_002289.2) - SHH141239 from Creative biogene
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Human Lysozyme-like protein 7 siRNA - orb263148 from Biorbyt
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LALBA shRNA Plasmid (Human) - CHH2646 from Cohesion Biosciences
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LALBA miRNA 3'UTR clone - MiUTR1H-05555 from Creative biogene
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