Gene Symbol |
LALBA
|
Entrez Gene |
3906
|
Alt Symbol |
-
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
lactalbumin, alpha-
|
Other Description |
alpha-lactalbumin|lactose synthase B protein|lysozyme-like protein 7
|
Swissprots |
Q6FGX0 P00709 Q9UDK4
|
Accessions |
BAC06860 CAA28799 CAA28800 EAW57990 P00709 BC069103 AAH69103 BC112316 AAI12317 BC112318 AAI12319 BX281629 CR541987 CAG46784 CR542017 CAG46814 HQ258062 ADR82816 J00270 AAA60345 XM_006719395 XP_006719458 XM_011538342 XP_011536644 XM_011538343 XP_011536645 NM_002289 NP_002280
|
Function |
Regulatory subunit of lactose synthase, changes the substrate specificity of galactosyltransferase in the mammary gland making glucose a good acceptor substrate for this enzyme. This enables LS to synthesize lactose, the major carbohydrate component of milk. In other tissues, galactosyltransferase transfers galactose onto the N-acetylglucosamine of the oligosaccharide chains in glycoproteins.
|
Subcellular Location |
Secreted.
|
Tissue Specificity |
Mammary gland specific. Secreted in milk.
|
Top Pathways |
Galactose metabolism
|