Gene Symbol | GOT1 |
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Entrez Gene | 396967 |
Alt Symbol | CASPAT, cCAT |
Species | Pig |
Gene Type | protein-coding |
Description | glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1) |
Other Description | aspartate aminotransferase, cytoplasmic|cysteine aminotransferase, cytoplasmic|cysteine transaminase, cytoplasmic|glutamate oxaloacetate transaminase 1|transaminase A |
Swissprots | P00503 |
Accessions | CBF96123 CBN65917 CBN71750 CBV09643 P00503 AK230811 AK234797 M24088 AAA53531 NM_213927 NP_999092 |
Function | Biosynthesis of L-glutamate from L-aspartate or L- cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H(2)S via the action of 3- mercaptopyruvate sulfurtransferase (3MST). Hydrogen sulfide is an important synaptic modulator and neuroprotectant in the brain (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm. |
Top Pathways | Cysteine and methionine metabolism, Alanine, aspartate and glutamate metabolism, Phenylalanine metabolism, Biosynthesis of amino acids, Tyrosine metabolism |
Aspartate aminotransferase, cytoplasmic (GOT1), Pig, ELISA Kit - CSB-EL009679PI from ARP American Research Products
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Aspartate aminotransferase, cytoplasmic, GOT1, Pig, ELISA Kit - E1214p from ARP American Research Products
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glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1) , ELISA Kit - MBS941742 from MyBioSource
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Pig Aspartate aminotransferase, cytoplasmic(GOT1) ELISA kit - CSB-EL009679PI from Cusabio
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Porcine AST (Aspartate Aminotransferase) ELISA Kit - E-EL-P0618 from Iwai North America Inc.
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Pig Aspartate aminotransferase, cytoplasmic (GOT1) ELISA Kit - EKC38100 from Biomatik
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Pig Aspartate aminotransferase, cytoplasmic ELISA Kit - EKE55089 from Biomatik
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Porcine GOT1 ELISA Kit - E074201 from Biobool
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GOT1 ELISA Kit (Pig) (OKEH03909) - OKEH03909 from Aviva Systems Biology
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Pig Aspartate aminotransferase, cytoplasmic ELISA Kit - EK2978 from Signalway Antibody
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Aspartate aminotransferase, ELISA Kit - MBS9426814 from MyBioSource
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Aspartate aminotransferase, ELISA Kit - MBS2885010 from MyBioSource
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Pig GOT1 ELISA Kit - orb409582 from Biorbyt
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