Gene Symbol | DGCR6L |
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Entrez Gene | 85359 |
Alt Symbol | DGCR6 |
Species | Human |
Gene Type | protein-coding |
Description | DiGeorge syndrome critical region gene 6-like |
Other Description | DiGeorge syndrome critical region gene 6 like|diGeorge syndrome critical region 6-like protein|protein DGCR6L |
Swissprots | B3KMC0 A8K1N7 Q9BW33 D3DX29 Q9BY27 |
Accessions | EAX02972 EAX02973 EAX02974 Q9BY27 AF228708 AAK15585 AK001528 BAG50932 AK289952 BAF82641 AK307210 AK310899 BC000682 AAH00682 CR456361 CAG30247 CU013071 CAK54502 CU013359 CAK54801 KJ535014 AHW56653 XM_011530470 XP_011528772 NM_033257 NP_150282 |
Function | May play a role in neural crest cell migration into the third and fourth pharyngeal pouches. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:15821931}. Note=Predominantly nuclear. |
Tissue Specificity | Widely expressed in fetal and adult tissues. Highest expression in liver, heart and skeletal muscle. Lower levels in pancreas and placenta. Weak expression in brain. {ECO:0000269|PubMed:11157784, ECO:0000269|PubMed:15821931}. |
DGCR6L CRISPR/Cas9 KO Plasmid (h) - sc-413769 from Santa Cruz Biotechnology
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DGCR6L HDR Plasmid (h) - sc-413769-HDR from Santa Cruz Biotechnology
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DGCR6L Double Nickase Plasmid (h) - sc-413769-NIC from Santa Cruz Biotechnology
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DGCR6L Double Nickase Plasmid (h2) - sc-413769-NIC-2 from Santa Cruz Biotechnology
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DGCR6L CRISPR Activation Plasmid (h) - sc-413769-ACT from Santa Cruz Biotechnology
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DGCR6L CRISPR Activation Plasmid (h2) - sc-413769-ACT-2 from Santa Cruz Biotechnology
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DGCR6L Lentiviral Activation Particles (h) - sc-413769-LAC from Santa Cruz Biotechnology
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DGCR6L Lentiviral Activation Particles (h2) - sc-413769-LAC-2 from Santa Cruz Biotechnology
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DGCR6L siRNA (h) - sc-105291 from Santa Cruz Biotechnology
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DGCR6L shRNA Plasmid (h) - sc-105291-SH from Santa Cruz Biotechnology
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DGCR6L shRNA (h) Lentiviral Particles - sc-105291-V from Santa Cruz Biotechnology
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DGCR6L RNAi - H00085359-R01 from Novus Biologicals
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MISSION® esiRNA - EHU110211 from Sigma-Aldrich
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MISSION® esiRNA - EHU110501 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN7175 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7175 from Sigma-Aldrich
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DGCR6L siRNA (Human) - CRJ3784 from Cohesion Biosciences
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DGCR6L - MBS8218785 from MyBioSource
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shRNA set against Human DGCR6L (NM_033257.3) - SHH277425 from Creative biogene
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Human DGCR6L siRNA - orb274285 from Biorbyt
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DGCR6L shRNA Plasmid (Human) - CHJ3784 from Cohesion Biosciences
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DGCR6L miRNA 3'UTR clone - MiUTR3H-10619 from Creative biogene
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