BIRC3

Gene Symbol BIRC3
Entrez Gene 330
Alt Symbol AIP1, API2, CIAP2, HAIP1, HIAP1, MALT2, MIHC, RNF49, c-IAP2
Species Human
Gene Type protein-coding
Description baculoviral IAP repeat containing 3
Other Description IAP homolog C|IAP-1|RING finger protein 49|TNFR2-TRAF signaling complex protein|TNFR2-TRAF-signaling complex protein 1|apoptosis inhibitor 2|baculoviral IAP repeat-containing 3|baculoviral IAP repeat-containing protein 3|inhibitor of apoptosis protein 1|mammalian IAP homolog C
Swissprots Q9HC27 Q9UP46 Q13489 Q16628
Accessions AAG09369 AAU88144 CBX47599 CBX47600 EAW67017 Q13489 AA805622 AA873008 AF070674 AAC83232 AI880555 BC027485 BC037420 AAH37420 BE907592 BG569841 BQ718651 BU428906 BX415415 BX475964 L43346 L49432 AAC41943 U37546 AAC50507 U45878 AAC50371 XM_011542797 XP_011541099 NM_001165 NP_001156 NM_182962 NP_892007
Function Multi-functional protein which regulates not only caspases and apoptosis, but also modulates inflammatory signaling and immunity, mitogenic kinase signaling and cell proliferation, as well as cell invasion and metastasis. Acts as an E3 ubiquitin- protein ligase regulating NF-kappa-B signaling and regulates both canonical and non-canonical NF-kappa-B signaling by acting in opposite directions: acts as a positive regulator of the canonical pathway and suppresses constitutive activation of non-canonical NF-kappa-B signaling. The target proteins for its E3 ubiquitin- protein ligase activity include: RIPK1, RIPK2, RIPK3, RIPK4, CASP3, CASP7, CASP8, IKBKE, TRAF1, and BCL10. Acts as an important regulator of innate immune signaling via regulation of Toll-like receptors (TLRs), Nodlike receptors (NLRs) and RIG-I like receptors (RLRs), collectively referred to as pattern recognition receptors (PRRs). Protects cells from spontaneous formation of the ripoptosome, a large multi-protein complex tha
Subcellular Location Cytoplasm {ECO:0000269|PubMed:15665297}. Nucleus {ECO:0000269|PubMed:15665297}.
Tissue Specificity Highly expressed in fetal lung, and kidney. In the adult, expression is mainly seen in lymphoid tissues, including spleen, thymus and peripheral blood lymphocytes.
Top Pathways NOD-like receptor signaling pathway, TNF signaling pathway, Toxoplasmosis, Apoptosis, Small cell lung cancer

Human BIRC3 / cIAP2 ELISA Kit (Sandwich ELISA) - LS-F56 from LifeSpan Bioscience

Category ELISA Kit
Prices $620.00, $1,090.00, $2,380.00
Sizes 1 plate, 2 plate, 5 plate
Sensitivity 1.024 ng/ml
Range 1.024-100 ng/ml

Human cIAP-2 ELISA Kit - RAB0027 from Sigma-Aldrich

Category ELISA Kit
Prices $850.00
Sizes 1 kt

Baculoviral IAP repeat-containing protein 3 (BIRC3), Human, ELISA Kit - E01B0800 from ARP American Research Products

Category ELISA Kit
Prices $535.00, $735.00
Sizes 48 t, 96 t

Human cIAP2 ELISA - ELH-cIAP2 from RayBiotech

Category ELISA Kit
Prices $560.00, $1,008.00, $2,241.00
Sizes 1 plate kit, 2 plate kit, 5 plate kit
Sensitivity 1 ng/ml
Range 1 ng/ml - 250 ng/ml
Human cIAP-2 ELISA Standard Curve

Baculoviral IAP repeat containing protein 3 (BIRC3), ELISA Kit - MBS7235955 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

baculoviral IAP repeat-containing 3, ELISA Kit - MBS928343 from MyBioSource

Category ELISA Kit
Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00
Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity 9.4 pg/ml
Range 37.5 pg/ml-2400 pg/ml

Baculoviral IAP repeat-containing protein 3 (BIRC3), ELISA Kit - MBS7200058 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Baculoviral IAP repeat-containing protein 3 (BIRC3), ELISA Kit - MBS7220032 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Baculoviral IAP repeat-containing protein 3 (BIRC3), ELISA Kit - MBS7244115 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Baculoviral IAP repeat-containing protein 3 (BIRC3), ELISA Kit - MBS7212116 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Baculoviral IAP repeat-containing protein 3 (BIRC3), ELISA Kit - MBS7250521 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Baculoviral IAP repeat-containing protein 3 (BIRC3), ELISA Kit - MBS7221354 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Baculoviral IAP repeat-containing protein 3 (BIRC3), ELISA Kit - MBS7244711 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Baculoviral IAP repeat-containing protein 3 (BIRC3), ELISA Kit - MBS7252940 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Baculoviral IAP repeat-containing protein 3 (BIRC3), ELISA Kit - MBS7209173 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity 0.1 ng/mL.

Baculoviral IAP repeat-containing protein 3 (BIRC3), ELISA Kit - MBS7227365 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Baculoviral IAP repeat-containing protein 3 (BIRC3), ELISA Kit - MBS7209726 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Human Baculoviral IAP repeat-containing protein 3(BIRC3) ELISA kit - CSB-EL002704HU from Cusabio

Category ELISA Kit
Sensitivity 9.4pg/ml
Range 37.5 pg/ml-2400 pg/ml

Human cIAP2 ELISA kit - orb78727 from Biorbyt

Category ELISA Kit
Prices $1,054.00, $1,811.00, $3,910.00
Sizes 96 well, 192 assays, 480 assays

Human cIAP2 ELISA - ELH-cIAP2-1 from RayBiotech

Category ELISA Kit
Prices $571.00, $1,027.80, $2,284.00
Sizes 1 plate kit, 2 plate kit, 5 plate kit

Human BIRC3 ELISA Kit - E004420 from Biobool

Category ELISA Kit
Sensitivity 9.4 pg/ml

anti-cIAP2 antibody - ARG54110 from Arigo Biolaboratories

Category ELISA Kit

BIRC3 ELISA Kit (Human) (OKCA01116) - OKCA01116 from Aviva Systems Biology

Category ELISA Kit
Prices $600.00
Sizes 96 wells
Sensitivity 9.4 pg/mL
Range 37.5 - 2,400 pg/mL
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