Gene Symbol | AS3MT |
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Entrez Gene | 57412 |
Alt Symbol | CYT19 |
Species | Human |
Gene Type | protein-coding |
Description | arsenite methyltransferase |
Other Description | S-adenosyl-L-methionine:arsenic(III) methyltransferase|S-adenosylmethionine:arsenic (III) methyltransferase|arsenic (+3 oxidation state) methyltransferase|methylarsonite methyltransferase|methyltransferase cyt19 |
Swissprots | Q5PZ02 A6NP79 Q0VDK3 Q9HBK9 Q0VDK4 |
Accessions | AAV68045 EAW49668 EAW49669 Q9HBK9 AF226730 AAG09731 AK057833 AK225972 AK309737 AW139845 BC119637 AAI19638 BC119638 AAI19639 BC160057 AAI60057 DA368970 NM_020682 NP_065733 |
Function | Catalyzes the transfer of a methyl group from AdoMet to trivalent arsenicals producing methylated and dimethylated arsenicals. It methylates arsenite to form methylarsonate, Me- AsO(3)H(2), which is reduced by methylarsonate reductase to methylarsonite, Me-As(OH)2. Methylarsonite is also a substrate and it is converted into the much less toxic compound dimethylarsinate (cacodylate), Me(2)As(O)-OH (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm {ECO:0000250}. |
cyt19 (H-199) - sc-134784 from Santa Cruz Biotechnology
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cyt19 (F-9) - sc-377436 from Santa Cruz Biotechnology
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cyt19 (M-300) - sc-134785 from Santa Cruz Biotechnology
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cyt19 (N-19) - sc-47984 from Santa Cruz Biotechnology
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Anti-Cyt 19 antibody - ab113970 from Abcam
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Anti-Cyt 19 antibody - ab104342 from Abcam
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Anti-Cyt 19 antibody - ab167196 from Abcam
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Anti-AS3MT Antibody (aa143-192) - LS-C116359 from LifeSpan Bioscience
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Anti-AS3MT Antibody (aa2-14) IHC-plus⢠- LS-B4926 from LifeSpan Bioscience
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AS3MT Antibody - NBP1-85354 from Novus Biologicals
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AS3MT Antibody - NB100-1131 from Novus Biologicals
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AS3MT Antibody - NBP1-85355 from Novus Biologicals
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AS3MT Antibody - H00057412-B01P-50ug from Novus Biologicals
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CYT19 Polyclonal Antibody - bs-10633R from Bioss
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Anti-AS3MT antibody produced in rabbit - SAB2105717 from Sigma-Aldrich
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Anti-AS3MT antibody produced in rabbit - HPA017856 from Sigma-Aldrich
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Anti-AS3MT antibody produced in rabbit - HPA027708 from Sigma-Aldrich
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Anti-AS3MT (N-terminal) antibody produced in goat - SAB2501890 from Sigma-Aldrich
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AS3MT antibody - middle region (ARP48862_P050) - ARP48862_P050 from Aviva Systems Biology
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Cyt19--AS3MT-Antibody-N-Term - AF2292a from Abgent, a WuXi AppTec company
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CYT19 antibody - GTX24205 from GeneTex
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CYT 19 antibody - orb156519 from Biorbyt
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Goat Anti-Cyt19 / AS3MT Antibody (OAEB00367) - OAEB00367 from Aviva Systems Biology
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Anti-Cyt 19 Antibody - AC21-0279 from Abcore
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Anti-Cyt 19 Antibody (AMCA) - AC21-0279-01 from Abcore
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