| Gene Symbol |
GHR
|
| Entrez Gene |
408184
|
| Alt Symbol |
GHBP
|
| Species |
Chicken
|
| Gene Type |
protein-coding
|
| Description |
growth hormone receptor
|
| Other Description |
GH receptor|growth hormone binding protein|somatotropin receptor
|
| Swissprots |
Q6LDA0 Q02092
|
| Accessions |
AAG10251 AAG10252 AAP92122 AAR30954 AAR98865 CAD44842 Q02092 AF254949 AAG10253 DQ138367 AAZ67363 KC242241 AGG38006 KC242242 AGG38007 M74057 AAA48781 S60800 AAD13921 S60801 S68571 S68576 AAB29983 S83100 AAD14425 NM_001001293 NP_001001293
|
| Function |
Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to, and activates the JAK2/STAT5 pathway.
|
| Subcellular Location |
Cell membrane; Single-pass type I membrane protein. Note=On growth hormone binding, GHR is ubiquitinated, internalized, down-regulated and transported into a degradative or non-degradative pathway.
|
| Tissue Specificity |
Broad specificity.
|
| Top Pathways |
Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, Neuroactive ligand-receptor interaction
|