Gene Symbol | TUBB3 |
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Entrez Gene | 10381 |
Alt Symbol | CDCBM, CDCBM1, CFEOM3, CFEOM3A, FEOM3, TUBB4, beta-4 |
Species | Human |
Gene Type | protein-coding |
Description | tubulin, beta 3 class III |
Other Description | class III beta-tubulin|tubulin beta-3 chain|tubulin beta-4 chain|tubulin beta-III |
Swissprots | Q9BTZ0 A8K854 Q9BW10 Q13509 |
Accessions | EAW66669 EAW66674 EAW66675 Q13509 AF427491 AAL28094 AK058140 AK122757 BAG53710 AK127418 AK223039 BAD96759 AK292219 BAF84908 AK307201 AK314616 BAG37182 AU142509 BC000748 AAH00748 BC001678 AAH01678 BC003021 AAH03021 BC047518 AAH47518 BC064975 CD621827 DA054466 S62643 U47634 AAC52035 NM_001197181 NP_001184110 NM_006086 NP_006077 |
Function | Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. TUBB3 plays a critical role in proper axon guidance and mantainance. {ECO:0000269|PubMed:20074521}. |
Subcellular Location | Cytoplasm, cytoskeleton. |
Tissue Specificity | Expression is primarily restricted to central and peripheral nervous system. Greatly increased expression in most cancerous tissues. {ECO:0000269|PubMed:14736079, ECO:0000269|PubMed:20191564}. |
Top Pathways | Gap junction, Pathogenic Escherichia coli infection, Phagosome |
Human beta III Tubulin full length protein - ab131995 from Abcam
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Human beta III Tubulin full length protein - ab140581 from Abcam
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Human beta III Tubulin peptide - ab18660 from Abcam
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Human beta III Tubulin protein fragment - ab125990 from Abcam
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TUBB3 / Tubulin Beta 3 Antibody Blocking Peptide - LS-E23264 from LifeSpan Bioscience
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TUBB3 / Tubulin Beta 3 Antibody Blocking Peptide - LS-E23265 from LifeSpan Bioscience
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TUBB3 / Tubulin Beta 3 Antibody Blocking Peptide - LS-E27963 from LifeSpan Bioscience
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Tubulin Beta 3 Recombinant Protein - H00010381-P01 from Novus Biologicals
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beta-III Tubulin Partial Recombinant Protein - H00010381-Q01 from Novus Biologicals
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Recombinant Human beta-III Tubulin Protein - NBP2-22901 from Novus Biologicals
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TUBB3-Antibody-N-term-Blocking-peptide - BP5752a from Abgent, a WuXi AppTec company
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Recombinant human Tubulin beta-3 chain protein (OPCA00527) - OPCA00527 from Aviva Systems Biology
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Human TUBB3 protein - orb245193 from Biorbyt
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Human Tubulin beta 3 protein - orb191042 from Biorbyt
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Human Tubulin Beta 3 Protein - abx069520 from Abbexa
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Beta III tubulin Peptide - AC21-2728-P from Abcore
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TUBB3 / TUBB4 (1-450, His-tag) - AR50820PU-N from Acris Antibodies
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TUBB3 / TUBB4 (1-450, His-tag) - AR50820PU-S from Acris Antibodies
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TUBB3 / TUBB4 - H00010381-P01-10 from Acris Antibodies
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TUBB3 / TUBB4 - H00010381-P01-25 from Acris Antibodies
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TUBB3 / TUBB4 - H00010381-Q01-10 from Acris Antibodies
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TUBB3 / TUBB4 - H00010381-Q01-25 from Acris Antibodies
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TUBB3, 1-450aa, Human, His tag, E.coli - 01-P1996 from ARP American Research Products
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Tubulin Beta 3 (TUBb3), Human - 20-8973 from ARP American Research Products
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TUBB3 Peptide - 43-094P from ProSci
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