SH3BP2

Gene Symbol SH3BP2
Entrez Gene 6452
Alt Symbol 3BP-2, 3BP2, CRBM, CRPM, RES4-23
Species Human
Gene Type protein-coding
Description SH3-domain binding protein 2
Other Description Abl-SH3 binding protein 2|SH3 domain-binding protein 2|TNFAIP3 interacting protein 2
Swissprots D3DVR0 B4DT04 A6NNC2 D6R919 P78315 P78314 B2R5R6 O15373 O00500
Accessions CAH05621 EAW82506 EAW82507 EAW82508 EAW82509 EAW82510 EAW82511 EAW82512 EAW82513 P78314 AB000462 BAA19119 AB000463 BAA19120 AF000936 AAB59973 AK124073 BAC85767 AK126537 BAC86582 AK225497 AK299996 BAG61816 AK304752 BAH14252 AK307106 AK312286 BAG35213 BC022996 AAH22996 DC391267 U56386 AAB72034 XM_005247998 XP_005248055 XM_005247999 XP_005248056 XM_011513547 XP_011511849 XM_011513548 XP_011511850 XM_011513549 XP_011511851 XM_011513550 XP_011511852 XM_011513551 XP_011511853 XM_011513552 XP_011511854 XM_011513553 XP_011511855 XM_011513554 XP_011511856 XM_011513555 XP_011511857 XM_011513556 XP_011511858 XR_924990 NM_001122681 NP_001116153 NM_001145855 NP_001139327 NM_001145856 NP_001139328 NM_003023 NP_003014
Function Binds differentially to the SH3 domains of certain proteins of signal transduction pathways. Binds to phosphatidylinositols; linking the hemopoietic tyrosine kinase fes to the cytoplasmic membrane in a phosphorylation dependent mechanism.
Tissue Specificity Expressed in a variety of tissues including lung, liver, skeletal muscle, kidney and pancreas. {ECO:0000269|PubMed:9734812}.
Top Pathways Natural killer cell mediated cytotoxicity

3BP2 (E-3) - sc-166636 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
3BP2 (E-3): sc-166636. Western blot analysis of 3BP2 expression in Jurkat (A), COLO 320DM (B) and MOLT-4 (C) whole cell lysates.

3BP2 (C-11) - sc-377020 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
3BP2 (C-11): sc-377020. Immunoperoxidase staining of formalin fixed, paraffin-embedded human upper stomach tissue showing cytoplasmic staining of glandular cells.

3BP2 (C-5) - sc-166459 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
3BP2 (C-5): sc-166459. Western blot analysis of 3BP2 expression in non-transfected: sc-117752 (A) and human 3BP2 transfected: sc-113954 (B) 293T whole cell lysates.

3BP2 (C-19) - sc-8897 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
3BP2 (C-19): sc-8897. Western blot analysis of 3BP2 expression in non-transfected: sc-117752 (A) and human 3BP2 transfected: sc-113954 (B) 293T whole cell lysates.

3BP2 (H-300) - sc-33567 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
3BP2 (H-300): sc-33567. Western blot analysis of 3BP2 expression in MOLT-4 (A), Jurkat (B), Raji (C) and HeLa (D) whole cell lysates.

Anti-SH3BP2 (phospho S427) antibody - ab2176 from Abcam

Prices $242.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-SH3BP2 antibody - ab84297 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-SH3BP2 antibody (ab84297) at 1 µg/ml (in 5% skim milk / PBS buffer) + 721_B cell lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-SH3BP2 antibody - ab55696 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-SH3BP2 antibody - ab117767 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-SH3BP2 antibody (ab117767) at 0.1 µg/mlLane 1 : HeLa whole cell lysate at 50 µgLane 2 : HeLa whole cell lysate at 15 µgdeveloped using the ECL technique

Anti-SH3BP2 antibody - ab130328 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-SH3BP2 antibody (ab130328) at 1/100 dilution + Mouse spleen lysate at 35 µg

Anti-SH3BP2 antibody - ab117833 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Detection of Human SH3BP2 by Immunoprecipitation of HeLa whole cell lysate (1 mg for IP, 20% of IP loaded) using ab117833 at 6 µg/mg of lysate. Subsequent WB detection was done using an other anti Human SH3BP2 antibody. Detection: Chemiluminescence with an exposure time of 10 seconds.

Anti-SH3BP2 antibody - ab172319 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-SH3BP2 antibody (ab172319) at 1 µg/mlLane 1 : SH3BP2 transfected 293T cell line lysateLane 2 : Non-transfected 293T cell line lysateLysates/proteins at 15 µl per lane.SecondaryGoat anti-Mouse IgGdeveloped using the ECL technique

Anti-SH3BP2 Antibody (phospho-Ser427) - LS-C10113 from LifeSpan Bioscience

Prices $515.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-SH3BP2 Antibody (phospho-Ser427) - LS-C91351 from LifeSpan Bioscience

Prices $575.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-SH3BP2 Antibody (aa150-180, AP) - LS-C269281 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SH3BP2 Antibody (aa150-180, APC) - LS-C269282 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SH3BP2 Antibody (aa150-180, Biotin) - LS-C269283 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SH3BP2 Antibody (aa150-180, FITC) - LS-C269284 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SH3BP2 Antibody (aa150-180, Azide-free, HRP) - LS-C269285 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SH3BP2 Antibody (aa150-180, PE) - LS-C269286 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SH3BP2 Antibody (phospho-Ser427) - LS-C18896 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-SH3BP2 pS427 Antibody - Western Blot. Western blot analysis is shown using Affinity Purified anti-SH3BP2 pS427 antibody to detect endogenous protein present in unstimulated human whole cell lysates). The band as indicated by the arrowheads is evident in both M059 cells (panel A) and PC-3 cells (panel B). Comparison to a molecular weight marker indicates a band of ~60 kD corresponding to human SH3BP2 protein. The blot was incubated with a 1:500 dilution of the antibody at room temperature followed by detection using standard techniques. Personal communication Steven Pelech, Kinexus Inc.

Anti-SH3BP2 Antibody (aa400-450) - LS-C289973 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-SH3BP2 Antibody (aa150-200) - LS-C289972 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-SH3BP2 Antibody (aa452-561, Azide-free) - LS-C328639 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal

Anti-SH3BP2 Antibody (aa150-180) - LS-C325086 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
Search more