SLC9A1

Gene Symbol	SLC9A1
Entrez Gene	6548
Alt Symbol	APNH, LIKNS, NHE-1, NHE1, PPP1R143
Species	Human
Gene Type	protein-coding
Description	solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
Other Description	Na(+)/H(+) exchanger 1|Na-Li countertransporter|protein phosphatase 1, regulatory subunit 143|sodium/hydrogen exchanger 1|solute carrier family 9 (sodium/hydrogen exchanger), isoform 1 (antiporter, Na+/H+, amiloride sensitive)|solute carrier family 9 (sodium/hydrogen exchanger), member 1 (antiporter, Na+/H+, amiloride sensitive)
Swissprots	B1ALD6 Q96EM2 P19634 D3DPL4
Accessions	CBX47581 EAX07773 EAX07774 EAX07775 P19634 AF141350 AAF21350 AF141351 AAF21351 AF141352 AAF21352 AF141353 AAF21353 AF141354 AAF21354 AF141355 AAF21355 AF141356 AAF21356 AF141357 AAF21357 AF141358 AAF21358 AF141359 AAF21359 AF146430 AAF25592 AF146431 AAF25593 AF146432 AAF25594 AF146433 AAF25595 AF146434 AAF25596 AF146435 AAF25597 AF146436 AAF25598 AF146437 AAF25599 AF146438 AAF25600 AF146439 AAF25601 AK096921 AK124218 AK300432 BAG62158 AK314190 BAG36869 BC012121 AAH12121 BC030272 BC090942 BQ775239 BQ775318 DA313453 DA853045 JF432248 ADZ15465 M81768 AAB59460 M96066 M96067 S68616 AAC60606 XM_011542021 XP_011540323 NM_003047 NP_003038 NR_046474
Function	Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Plays an important role in signal transduction. {ECO:0000269|PubMed:11350981, ECO:0000269|PubMed:15035633, ECO:0000269|PubMed:8901634}.
Subcellular Location	Membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Cell membrane; Multi-pass membrane protein. Note=Colocalizes with CHP1 at the reticulum endoplasmic (By similarity). Colocalizes with CHP1 and CHP2 at the plasma membrane. {ECO:0000250}.
Tissue Specificity	Kidney and intestine.
Top Pathways	Bile secretion, Pancreatic secretion, Gastric acid secretion, Adrenergic signaling in cardiomyocytes, Salivary secretion

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Sodium / Hydrogen Exchanger 1 protein fragment - ab152688 from Abcam Category Protein Source Wheat germ Species Human

SLC9A1 / NHE1 Antibody Blocking Peptide - LS-E16118 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SLC9A1 / NHE1 Antibody Blocking Peptide - LS-E30411 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

SLC9A1 / NHE1 Antibody Blocking Peptide - LS-E30410 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

Recombinant Human NHE1/SLC9A1 Protein - H00006548-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

NHE1/SLC9A1 Blocking Peptide - NBP1-76848PEP from Novus Biologicals Category Peptide Prices $129.00 Sizes 50 µg Species Human

NHE1/SLC9A1 Blocking Peptide - NBP1-76847PEP from Novus Biologicals Category Peptide Prices $129.00 Sizes 50 µg Species Human

Recombinant Human NHE1/SLC9A1 Protein - H00006548-G01-10ug from Novus Biologicals Category Protein Prices $569.00 Sizes 10 µg Species Human

SLC9A1-Antibody-Center-Blocking-Peptide - BP18823c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

NHE-1 Peptide - GTX85046-PEP from GeneTex Category Peptide Prices $149.00 Sizes 50 μg Species Human

NHE-1 Peptide - GTX85047-PEP from GeneTex Category Peptide Prices $149.00 Sizes 50 μg Species Human

SLC9A1 Blocking Peptide - 33R-8187 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

SLC9A1 / NHE1 - H00006548-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

SLC9A1 / NHE1 - H00006548-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

SLC9A1 / NHE1 Control Peptide - AP05294CP-N from Acris Antibodies Category Peptide Prices $205.00 Sizes 50 µg

SLC9A1 / NHE1 Control Peptide - AP30591CP-N from Acris Antibodies Category Peptide Prices $135.00 Sizes 50 µg

SLC9A1 / NHE1 Control Peptide - AP30592CP-N from Acris Antibodies Category Peptide Prices $135.00 Sizes 50 µg

Nhe-1 Peptide - 4379P from ProSci Category Peptide Species Human

Nhe-1 Peptide - 4377P from ProSci Category Peptide Species Human

NHE1 fusion protein - ag14324 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

NHE1 fusion protein - Ag14329 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

Recombinant Sodium/Hydrogen Exchanger 1 (NHE1) - RPE411Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Na+/H+ Exchanger-1, Control Peptide for AB3081/AB3082 - AG345 from EMD Millipore Category Peptide Prices $226.00 Sizes 100 µg

Recombinant Sodium/Hydrogen Exchanger 1 (NHE1) - RPE411Hu01 from Cloud-clone Category Protein Source E.coli Species Human

SLC9A1 Peptide (OEEG01154) - OEEG01154 from Aviva Systems Biology Category Peptide Prices $150.00 Sizes 50 µg Source Rabbit Species Human

Search more