Gene Symbol | AP1M2 |
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Entrez Gene | 10053 |
Alt Symbol | AP1-mu2, HSMU1B, MU-1B, MU1B, mu2 |
Species | Human |
Gene Type | protein-coding |
Description | adaptor-related protein complex 1, mu 2 subunit |
Other Description | AP-1 complex subunit mu-2|AP-mu chain family member mu1B|HA1 47 kDa subunit 2|adaptor protein complex AP-1 mu-2 subunit|clathrin assembly protein complex 1 mu-2 medium chain 2|clathrin coat assembly protein AP47 2|clathrin coat associated protein AP47 2|clathrin-associated adaptor medium chain mu2|golgi adaptor AP-1 47 kDa protein|golgi adaptor HA1/AP1 adaptin mu-2 subunit|mu-adaptin 2|mu1B-adaptin |
Swissprots | Q9BSI8 Q9Y6Q5 B2RDV5 |
Accessions | EAW84124 EAW84125 Q9Y6Q5 AF020797 AAD25870 AK023863 BAG51230 AK222946 BAD96666 AK315689 BAG38052 AW370781 BC003387 AAH03387 BC003612 AAH03612 BC005021 AAH05021 BE044092 HQ447268 ADQ31755 XM_011527615 XP_011525917 NM_001300887 NP_001287816 NM_005498 NP_005489 |
Function | Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. |
Subcellular Location | Golgi apparatus. Cytoplasmic vesicle, clathrin-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Note=Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex. |
Top Pathways | Lysosome |
AP-1μ2 CRISPR/Cas9 KO Plasmid (h) - sc-404512 from Santa Cruz Biotechnology
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AP-1μ2 HDR Plasmid (h) - sc-404512-HDR from Santa Cruz Biotechnology
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AP-1μ2 Double Nickase Plasmid (h) - sc-404512-NIC from Santa Cruz Biotechnology
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AP-1μ2 Double Nickase Plasmid (h2) - sc-404512-NIC-2 from Santa Cruz Biotechnology
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AP-1μ2 CRISPR Activation Plasmid (h) - sc-404512-ACT from Santa Cruz Biotechnology
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AP-1μ2 CRISPR Activation Plasmid (h2) - sc-404512-ACT-2 from Santa Cruz Biotechnology
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AP-1μ2 Lentiviral Activation Particles (h) - sc-404512-LAC from Santa Cruz Biotechnology
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AP-1μ2 Lentiviral Activation Particles (h2) - sc-404512-LAC-2 from Santa Cruz Biotechnology
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AP-1µ2 siRNA (h) - sc-72509 from Santa Cruz Biotechnology
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AP-1µ2 shRNA Plasmid (h) - sc-72509-SH from Santa Cruz Biotechnology
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AP-1µ2 shRNA (h) Lentiviral Particles - sc-72509-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU154601 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN3283 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3283 from Sigma-Aldrich
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AP1M2 siRNA (Human) - CRH6769 from Cohesion Biosciences
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AP1M2 - MBS8223422 from MyBioSource
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shRNA set against Human AP1M2 (NM_005498.4) - SHH237778 from Creative biogene
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Human AP1M2 siRNA - orb267271 from Biorbyt
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AP1M2 shRNA Plasmid (Human) - CHH6769 from Cohesion Biosciences
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AP1M2 miRNA 3'UTR clone - MiUTR3H-09131 from Creative biogene
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