ACTL6A

Gene Symbol	ACTL6A
Entrez Gene	86
Alt Symbol	ACTL6, ARPN-BETA, Arp4, BAF53A, INO80K
Species	Human
Gene Type	protein-coding
Description	actin-like 6A
Other Description	53 kDa BRG1-associated factor A|BAF complex 53 kDa subunit|BAF53|BRG1-associated factor 53A|INO80 complex subunit K|actin-like protein 6A|actin-related protein 4|actin-related protein Baf53a|arpNbeta|hArpN beta
Swissprots	O96019 B3KMN1 Q8TAE5 Q9BVS8 Q9H0W6 D3DNR9
Accessions	EAW78397 EAW78398 EAW78399 EAW78400 EAW78401 O96019 AA256726 AB015907 BAA74577 AB060168 BAB87844 AB061315 BAB87848 AF041474 AAC94991 AK021756 BAG51043 AK098691 AK223212 BAD96932 AL136608 CAB66543 BC000949 AAH00949 BC001391 AAH01391 BC035463 BC036371 AAH36371 CR533529 CAG38560 DB041143 EU832285 ACE87542 EU832370 ACE86855 HQ448270 ADQ32750 NM_004301 NP_004292 NM_177989 NP_817126 NM_178042 NP_829888
Function	Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Required for maximal ATPase activity of SMARCA4/BRG1/BAF190A and for association of the SMARCA4/BRG1/BAF190A containing remodeling complex BAF with chromatin/nuclear matrix. Belongs to the neural progenitors- specific chromatin remodeling complex (npBAF complex) and is required for the proliferation of neural progenitors. During neural development a switch from a stem/progenitor to a post- mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF
Subcellular Location	Nucleus {ECO:0000269|PubMed:18026119}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human ACTL6A full length protein - ab134842 from Abcam Category Protein Source E. coli Species Human

Human BAF53A full length protein - ab38181 from Abcam Category Protein Prices $297.00 Sizes 10 µg Source E. coli Species Human

Human BAF53A peptide - ab13770 from Abcam Category Peptide Prices $181.00 Sizes 100 µg

Human BAF53A peptide - ab23271 from Abcam Category Peptide Prices $181.00 Sizes 100 µg Species Human

BAF53 / ACTL6A Antibody Blocking Peptide - LS-E4640 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

BAF53 / ACTL6A Antibody Blocking Peptide - LS-E11764 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

BAF53A / BAF53B Antibody Blocking Peptide - LS-E25711 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human BAF53A Protein - H00000086-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human BAF53A Protein - H00000086-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human BAF53A Protein - H00000086-P02 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

ACTL6A-Antibody-N-term-Blocking-Peptide - BP17002a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

ACTL6A Recombinant Protein - GTX48230-PRO from GeneTex Category Protein Prices $329.00 Sizes 50 μg Source E. coli Species Human

BAF53A and BAF53B blocking peptide - GTX89742-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Dog, Rat, Bovine

ACTL6A Protein (OPPA01291) - OPPA01291 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 2 µg Source E. Coli

Human Actin-Like 6A protein - orb80899 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 2 μg, 10 μg Source E.coli

ACTL6A Blocking Peptide - 33R-9460 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

BAF53A Blocking Peptide - abx062003 from Abbexa Category Peptide Species Human, Mouse, Rat, Bovine, Chicken, Dog, Pig

ACTL6A / BAF53 - H00000086-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

ACTL6A / BAF53 - H00000086-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

ACTL6A / BAF53 - H00000086-P02 from Acris Antibodies Category Protein Prices $370.00 Sizes 10 µg Species Human

ACTL6A / BAF53 - H00000086-P02-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

ACTL6A / BAF53 - H00000086-P02-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

ACTL6A / BAF53 - H00000086-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

ACTL6A / BAF53 - H00000086-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

Recombinant Human ACTL6A - 228-10023-1 from RayBiotech Category Protein Prices $118.00 Sizes 1 µg Source Escherichia Coli. Species Human

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