Gene Symbol | Dffb |
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Entrez Gene | 13368 |
Alt Symbol | 40kDa, 5730477D02Rik, CAD, CPAN, DFF40, Didff |
Species | Mouse |
Gene Type | protein-coding |
Description | DNA fragmentation factor, beta subunit |
Other Description | DFF-40|DNA fragmentation factor 40 kDa subunit|DNA fragmentation factor subunit beta|DNA fragmentation factor, 40 kD, beta subunit|DNase inhibited by DNA fragmentation factor|caspase-activated DNase|caspase-activated deoxyribonuclease |
Swissprots | O54788 |
Accessions | EDL14950 O54788 AB009377 BAA24977 AK036094 AK077619 BAC36905 AK089267 BC053052 AAH53052 XM_006538517 XP_006538580 XM_011250183 XP_011248485 XM_011250184 XP_011248486 XM_011250185 XP_011248487 XM_011250186 XP_011248488 NM_007859 NP_031885 |
Function | Nuclease that induces DNA fragmentation and chromatin condensation during apoptosis. Degrades naked DNA and induces apoptotic morphology. |
Subcellular Location | Cytoplasm. Nucleus. |
Top Pathways | Apoptosis |
CAD CRISPR/Cas9 KO Plasmid (m) - sc-420001 from Santa Cruz Biotechnology
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CAD HDR Plasmid (m) - sc-420001-HDR from Santa Cruz Biotechnology
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CAD Double Nickase Plasmid (m) - sc-420001-NIC from Santa Cruz Biotechnology
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CAD Double Nickase Plasmid (m2) - sc-420001-NIC-2 from Santa Cruz Biotechnology
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CAD CRISPR Activation Plasmid (m) - sc-420001-ACT from Santa Cruz Biotechnology
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CAD CRISPR Activation Plasmid (m2) - sc-420001-ACT-2 from Santa Cruz Biotechnology
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CAD Lentiviral Activation Particles (m) - sc-420001-LAC from Santa Cruz Biotechnology
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CAD Lentiviral Activation Particles (m2) - sc-420001-LAC-2 from Santa Cruz Biotechnology
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CAD siRNA (m) - sc-29872 from Santa Cruz Biotechnology
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CAD shRNA Plasmid (m) - sc-29872-SH from Santa Cruz Biotechnology
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CAD shRNA (m) Lentiviral Particles - sc-29872-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EMU086981 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN29933 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND29933 from Sigma-Aldrich
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DFFB siRNA (Mouse) - CRM1028 from Cohesion Biosciences
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DFFB - MBS8213391 from MyBioSource
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CAD CRISPR/Cas9 KO Plasmid (m2) - sc-420001-KO-2 from Santa Cruz Biotechnology
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CAD HDR Plasmid (m2) - sc-420001-HDR-2 from Santa Cruz Biotechnology
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shRNA set against Mouse DFFB (NM_007859.4) - SHH277293 from Creative biogene
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shRNA set against Mouse Dffb(NM_007859.4) - SHH002243 from Creative biogene
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Mouse DFFB siRNA - orb280504 from Biorbyt
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DFFB shRNA Plasmid (Mouse) - CHM1028 from Cohesion Biosciences
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DFFB miRNA 3'UTR clone - MiUTR1M-03819 from Creative biogene
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