| Gene Symbol | IL2 |
|---|---|
| Entrez Gene | 403989 |
| Alt Symbol | - |
| Species | Dog |
| Gene Type | protein-coding |
| Description | interleukin 2 |
| Other Description | IL-2|T-cell growth factor|TCGF|interleukin-2 |
| Swissprots | Q28249 Q29416 |
| Accessions | Q29416 AF091131 AAD46989 AF329867 AAL26925 AF333117 AAK01437 AF333118 AAK01438 AM238655 CAJ87635 D30710 BAA06378 U11689 AAA75360 U28141 AAA68969 NM_001003305 NP_001003305 |
| Function | Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine- activated killer cells, natural killer cells, and glioma cells. |
| Subcellular Location | Secreted. |
| Top Pathways | Inflammatory bowel disease (IBD), Measles, PI3K-Akt signaling pathway, HTLV-I infection, Cytokine-cytokine receptor interaction |