Gene Symbol | SGSM3 |
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Entrez Gene | 27352 |
Alt Symbol | MAP, RABGAP5, RUSC3, RUTBC3, RabGAP-5, rabGAPLP |
Species | Human |
Gene Type | protein-coding |
Description | small G protein signaling modulator 3 |
Other Description | RUN and SH3 containing 3|RUN and TBC1 domain containing 3|RUN and TBC1 domain-containing protein 3|merlin binding protein|merlin-associated protein|rab-GTPase-activating protein-like protein|small G protein signaling modulator 3 protein |
Swissprots | Q7Z709 B0QY79 Q9NT69 Q96HU1 |
Accessions | EAW60378 EAW60379 EAW60380 EAW60381 Q96HU1 AB196956 BAE02561 AB275763 BAF63513 AB449880 BAH16623 AK000006 BAA92231 AK295469 BAG58399 AK297599 BAG59984 AK301042 BAG62655 AK309400 AL137499 CAB70773 AW512418 AY308849 AAQ81879 BC008078 AAH08078 BC127850 AAI27851 BG741967 BP283990 BU585020 CR456441 CAG30327 CU013039 CAK54470 CU013327 CAK54769 DQ893271 ABM84197 DQ896602 ABM87601 HY229847 XM_005261572 XP_005261629 XM_005261573 XP_005261630 XM_005261574 XP_005261631 XM_005261575 XP_005261632 XM_005261577 XP_005261634 XM_011530158 XP_011528460 XM_011530159 XP_011528461 XM_011530160 XP_011528462 XM_011530161 XP_011528463 XM_011530162 XP_011528464 XR_244369 XR_937841 XR_937842 NM_001301849 NP_001288778 NM_015705 NP_056520 |
Function | May play a cooperative role in NF2-mediated growth suppression of cells. {ECO:0000269|PubMed:15541357}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:15849434}. |
Tissue Specificity | Widely expressed. {ECO:0000269|PubMed:17509819}. |
SGSM3 CRISPR/Cas9 KO Plasmid (h) - sc-411999 from Santa Cruz Biotechnology
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SGSM3 HDR Plasmid (h) - sc-411999-HDR from Santa Cruz Biotechnology
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SGSM3 Double Nickase Plasmid (h) - sc-411999-NIC from Santa Cruz Biotechnology
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SGSM3 Double Nickase Plasmid (h2) - sc-411999-NIC-2 from Santa Cruz Biotechnology
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SGSM3 CRISPR Activation Plasmid (h) - sc-411999-ACT from Santa Cruz Biotechnology
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SGSM3 CRISPR Activation Plasmid (h2) - sc-411999-ACT-2 from Santa Cruz Biotechnology
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SGSM3 Lentiviral Activation Particles (h) - sc-411999-LAC from Santa Cruz Biotechnology
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SGSM3 Lentiviral Activation Particles (h2) - sc-411999-LAC-2 from Santa Cruz Biotechnology
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SGSM3 siRNA (h) - sc-76492 from Santa Cruz Biotechnology
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SGSM3 shRNA Plasmid (h) - sc-76492-SH from Santa Cruz Biotechnology
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SGSM3 shRNA (h) Lentiviral Particles - sc-76492-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU074011 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN19241 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19241 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR04358 from Sigma-Aldrich
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SGSM3 siRNA (Human) - CRH9101 from Cohesion Biosciences
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SGSM3 - MBS8214787 from MyBioSource
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shRNA set against Human SGSM3 (NM_015705.4) - SHH406420 from Creative biogene
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Human SGSM3 siRNA - orb269603 from Biorbyt
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SGSM3 shRNA Plasmid (Human) - CHH9101 from Cohesion Biosciences
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SGSM3 miRNA 3'UTR clone - MiUTR1H-09087 from Creative biogene
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