TFB2M

Gene Symbol TFB2M
Entrez Gene 64216
Alt Symbol Hkp1, mtTFB2
Species Human
Gene Type protein-coding
Description transcription factor B2, mitochondrial
Other Description HCV NS5A-transactivated protein 5|S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase 2|dimethyladenosine transferase 2, mitochondrial|h-mtTFB|h-mtTFB2|hTFB2M|hepatitis C virus NS5A-transactivated protein 5|mitochondrial 12S rRNA dimethylase 2|mitochondrial transcription factor B2
Swissprots Q9H626 Q9H5Q4
Accessions EAW77149 EAW77150 EAW77151 EAW77152 EAW77153 Q9H5Q4 AF529366 AAQ09600 AK026314 BAB15441 AK026835 BAB15566 AK300238 BAG62006 BC003383 AAH03383 CK725134 DA038232 EU446518 ABZ92047 XM_011544248 XP_011542550 NM_022366 NP_071761
Function S-adenosyl-L-methionine-dependent methyltransferase which specifically dimethylates mitochondrial 12S rRNA at the conserved stem loop. Also required for basal transcription of mitochondrial DNA, probably via its interaction with POLRMT and TFAM. Stimulates transcription independently of the methyltransferase activity. Compared to TFB1M, it activates transcription of mitochondrial DNA more efficiently, while it has less methyltransferase activity. {ECO:0000269|PubMed:12068295, ECO:0000269|PubMed:12897151, ECO:0000269|PubMed:15526033, ECO:0000269|PubMed:20410300}.
Subcellular Location Mitochondrion.
Tissue Specificity Ubiquitously expressed. {ECO:0000269|PubMed:12068295}.

TFB2M (N-13) - sc-160859 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

TFB2M (D-13) - sc-160856 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

TFB2M (X-23) - sc-134078 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal
TFB2M (X-23): sc-134078. Immunoperoxidase staining of formalin-fixed, paraffin-embedded human intestine tissue showing cytoplasmic localization.

Anti-TFB2M antibody - ab13676 from Abcam

Prices $370.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-TFB2M antibody - ab66014 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-TFB2M antibody (ab66014) at 1.25 µg/ml + transfected 293T cell lysate at 10 µg with 5% skim milk / PBS bufferSecondaryHRP conjugated anti-Rabbit IgG at 50,000 - 100,000 dilution

Anti-TFB2M antibody - ab88187 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Anti-TFB2M antibody (ab88187) at 1 µg/ml + Partial recombinant tagged TFB2M protein (Immunogen) at 0.1 µgSecondaryGoat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/5000 dilution

Anti-TFB2M antibody - ab116608 from Abcam

Prices $370.00
Sizes 200 µl
Host Goat
Clonality Polyclonal
Anti-TFB2M antibody (ab116608) at 0.1 µg/ml + Human Lung lysate at 35 µgdeveloped using the ECL technique

Anti-TFB2M antibody - ab107685 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-TFB2M antibody (ab107685) at 1/100 dilution + WiDr cell line lysates at 35 µg

Anti-TFB2M antibody - N-terminal - ab187115 from Abcam

Host Rabbit
Clonality Polyclonal
Anti-TFB2M antibody - N-terminal (ab187115) at 1/1000 dilution + HeLa total cell extract

Anti-TFB2M Antibody (aa101-150) - LS-C80090 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
TFB2M antibody LS-C80090 was used in IHC to stain formalin-fixed, paraffin-embedded human intestine.

Anti-TFB2M Antibody (aa368-396) - LS-C161818 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
TFB2M Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human heart carcinoma followed by peroxidase-conjugated secondary antibody and DAB staining.

Anti-TFB2M Antibody (aa81-94) - LS-C139799 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
TFB2M antibody (0.5 ug/ml) staining of Rat Lung lysate (35 ug protein/ml in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-TFB2M Antibody (aa383-396) IHC-plus™ - LS-B11146 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Anti-TFB2M antibody IHC staining of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B11146 concentration 5 ug/ml.

Anti-TFB2M Antibody (aa325-338) IHC-plus™ - LS-B10472 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Human, Colon: Formalin-Fixed Paraffin-Embedded (FFPE)

Anti-TFB2M Antibody (aa368-396, AP) - LS-C217934 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TFB2M Antibody (aa368-396, Biotin) - LS-C217936 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TFB2M Antibody (aa368-396, APC) - LS-C217935 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TFB2M Antibody (aa368-396, FITC) - LS-C217937 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TFB2M Antibody (aa368-396, Azide-free, HRP) - LS-C217938 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TFB2M Antibody (aa368-396, PE) - LS-C217939 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TFB2M Antibody (C-Terminus) - LS-C80268 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Transfected 293T cell lysate. Antibody concentration: 5.0 ug/ml. Gel concentration: 12%.

Anti-TFB2M Antibody (aa375-404) - LS-C325678 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TFB2M Antibody (N-Terminus) - LS-C116171 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
TFB2M antibody LS-C116171 Western blot of Fetal Spleen lysate.

TFB2M Antibody - NBP1-82114 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: TFB2M Antibody [NBP1-82114] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10. Lane 2: Negative control (vector only transfected HEK293T lysate). Lane 3: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).

TFB2M Antibody - H00064216-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
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