Gene Symbol | MGAT2 |
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Entrez Gene | 4247 |
Alt Symbol | CDG2A, CDGS2, GLCNACTII, GNT-II, GNT2 |
Species | Human |
Gene Type | protein-coding |
Description | mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase |
Other Description | Beta-1,2-N-acetylglucosaminyltransferase II|N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase II|UDP-N-acetylglucosamine:alpha-6-D-mannoside beta-1,2-N-acetylglucosaminyltransferase II|alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase|glcNAc-T II|mannoside acetylglucosaminyltransferase 2 |
Swissprots | B3KPC5 Q10469 B3KQM0 |
Accessions | AAA86956 CAL47688 EAW65758 Q10469 AK056167 BAG51637 AK075051 AK075199 BAG52082 AK293231 BAG56770 BC006390 AAH06390 BC018912 BI764270 BQ023756 DQ892713 ABM83639 DQ896859 ABM87858 NM_002408 NP_002399 NM_001015883 |
Function | Catalyzes an essential step in the conversion of oligo- mannose to complex N-glycans. |
Subcellular Location | Golgi apparatus membrane; Single-pass type II membrane protein. |
Top Pathways | N-Glycan biosynthesis |
GnT-II CRISPR/Cas9 KO Plasmid (h) - sc-407393 from Santa Cruz Biotechnology
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GnT-II HDR Plasmid (h) - sc-407393-HDR from Santa Cruz Biotechnology
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GnT-II Double Nickase Plasmid (h) - sc-407393-NIC from Santa Cruz Biotechnology
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GnT-II Double Nickase Plasmid (h2) - sc-407393-NIC-2 from Santa Cruz Biotechnology
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GnT-II CRISPR Activation Plasmid (h) - sc-407393-ACT from Santa Cruz Biotechnology
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GnT-II CRISPR Activation Plasmid (h2) - sc-407393-ACT-2 from Santa Cruz Biotechnology
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GnT-II Lentiviral Activation Particles (h) - sc-407393-LAC from Santa Cruz Biotechnology
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GnT-II Lentiviral Activation Particles (h2) - sc-407393-LAC-2 from Santa Cruz Biotechnology
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GnT-II siRNA (h) - sc-106777 from Santa Cruz Biotechnology
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GnT-II shRNA Plasmid (h) - sc-106777-SH from Santa Cruz Biotechnology
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GnT-II shRNA (h) Lentiviral Particles - sc-106777-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU013391 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN13273 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND13273 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR06928 from Sigma-Aldrich
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MGAT2 siRNA (Human) - CRH2887 from Cohesion Biosciences
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GnT-II CRISPR/Cas9 KO Plasmid (h2) - sc-407393-KO-2 from Santa Cruz Biotechnology
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GnT-II HDR Plasmid (h2) - sc-407393-HDR-2 from Santa Cruz Biotechnology
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shRNA set against Human MGAT2 (NM_002408.3) - SHH341351 from Creative biogene
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Human MGAT2 siRNA - orb263389 from Biorbyt
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MGAT2 shRNA Plasmid (Human) - CHH2887 from Cohesion Biosciences
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MGAT2 miRNA 3'UTR clone - MiUTR3H-05132 from Creative biogene
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