DNM2

Gene Symbol	DNM2
Entrez Gene	1785
Alt Symbol	CMT2M, CMTDI1, CMTDIB, DI-CMTB, DYN2, DYNII, LCCS5
Species	Human
Gene Type	protein-coding
Description	dynamin 2
Other Description	dynamin II|dynamin-2
Swissprots	A8K1B6 Q7Z5S3 Q9UPH4 Q5I0Y0 K7ESI9 E7EV30 P50570 E9PEQ4
Accessions	AAD23603 AAD23604 EAW84144 EAW84145 EAW84146 EAW84147 EAW84148 EAW84149 EAW84150 EAW84151 P50570 AB209213 BAD92450 AK023207 AK094984 BAG52966 AK097875 BAC05190 AK097967 AK097989 BAG53560 AK124881 BAC85978 AK126192 BAC86481 AK127033 BAC86797 AK289831 BAF82520 AK295929 BAG58715 AK312260 AY927542 BC039596 AAH39596 BC054501 AAH54501 BM148999 BU621654 DB069057 DQ594929 L36983 AAA88025 NM_001005360 NP_001005360 NM_001005361 NP_001005361 NM_001005362 NP_001005362 NM_001190716 NP_001177645 NM_004945 NP_004936
Function	Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Plays a role in the regulation of neuron morphology, axon growth and formation of neuronal growth cones (By similarity). Plays an important role in vesicular trafficking processes, in particular endocytosis. Involved in cytokinesis. {ECO:0000250|UniProtKB:P39052, ECO:0000269|PubMed:12498685}.
Subcellular Location	Cytoplasm. Cytoplasm, cytoskeleton. Cell junction {ECO:0000250|UniProtKB:P39052}. Membrane, clathrin-coated pit {ECO:0000250|UniProtKB:P39052}. Cell junction, synapse, postsynaptic cell membrane, postsynaptic density. Cell junction, synapse. Midbody. Note=Colocalizes with CTTN at the basis of filopodia in hippocampus neuron growth zones (By similarity). Microtubule-associated. Also found in the postsynaptic density of neuronal cells. {ECO:0000250|UniProtKB:P39052}.
Tissue Specificity	Ubiquitously expressed.
Top Pathways	Fc gamma R-mediated phagocytosis, Endocytosis, Bacterial invasion of epithelial cells, Endocrine and other factor-regulated calcium reabsorption, Synaptic vesicle cycle

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

DNM2 overexpression lysate - LY417632 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

DNM2 overexpression lysate - LY423697 from Acris Antibodies Category Cell Lysate Prices $480.00 Sizes 100 µg

DNM2 overexpression lysate - LY429232 from Acris Antibodies Category Cell Lysate Prices $480.00 Sizes 100 µg

DNM2 293 Cell Lysate - 409983 from ABBIOTEC Category Cell Lysate Prices $672.00 Sizes 100 µg

DNM2 Over-expression Lysate Product - GWB-160CEE from Genway Biotech Category Cell Lysate Prices $756.00 Sizes 100 µg Species Human

Dynamin 2 Overexpression Lysate (Native) - NBP2-11313 from Novus Biologicals Category Cell Lysate Prices $529.00 Sizes 100 µg

Dynamin 2 Overexpression Lysate (Native) - NBP2-10512 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

Panoply™ Human DNM2 Knockdown Stable Cell Line - CSC-DC004459 from Creative biogene Category Cell Line Species Human

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