NPPB

Gene Symbol NPPB
Entrez Gene 4879
Alt Symbol BNP
Species Human
Gene Type protein-coding
Description natriuretic peptide B
Other Description brain type natriuretic peptide|gamma-brain natriuretic peptide|natriuretic peptide precursor B|natriuretic peptides B|natriuretic protein
Swissprots Q9P2Q7 B0ZBE9 P16860 Q6FGY0
Accessions AAA35603 ACA05917 BAA04067 BAA90441 BAD06457 BAF64842 EAW71718 EAW71719 P16860 AJ708502 BC025785 AAH25785 CR541976 CAG46774 CR542003 CAG46800 M25296 AAA36355 NM_002521 NP_002512
Function Cardiac hormone which may function as a paracrine antifibrotic factor in the heart. Also plays a key role in cardiovascular homeostasis through natriuresis, diuresis, vasorelaxation, and inhibition of renin and aldosterone secretion. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3. {ECO:0000269|PubMed:1672777}.
Subcellular Location Secreted.
Tissue Specificity Brain and also in atria, but at much lower levels than ANP.
Top Pathways cGMP-PKG signaling pathway

Human BNP full length protein - ab151881 from Abcam

Category Protein
Prices $188.00
Sizes 10 µg
Source E. coli
Species Human

Human BNP full length protein - ab87200 from Abcam

Category Protein
Prices $228.00, $866.00
Sizes 100 µg, 500 µg
Source E. coli
Species Human
15% SDS-PAGE showing ab87200 at approximately 14kDa (3µg).

Human BNP peptide - ab123777 from Abcam

Category Peptide
Prices $522.00
Sizes 1 mg
Species Human

Human BNP peptide - ab42276 from Abcam

Category Peptide
Prices $181.00
Sizes 100 µg
Species Human

Human BNP protein fragment - ab200273 from Abcam

Category Protein
Prices $101.00
Sizes 20 µg
Source E. coli
Species Human

Human proBNP peptide - ab42238 from Abcam

Category Peptide
Species Human

Human proBNP protein fragment - ab51403 from Abcam

Category Protein
Source E. coli
Species Human

Human BNP Protein - NBP2-34936 from Novus Biologicals

Category Protein
Prices $75.00
Sizes 20 µg
Source Escherichia coli.
Species Human

BNP Recombinant Protein - H00004879-P01 from Novus Biologicals

Category Protein
Prices $319.00
Sizes 2 µg
Species Human

Recombinant Human proBNP Protein - NBC1-18491 from Novus Biologicals

Category Protein
Prices $269.00
Sizes 100 µg
Species Human
SDS-Page: proBNP Protein [NBC1-18491] - BNP, 14 kDa (129 aa), confirmed by MALDI-TOF with a purity of 90% by SDS - PAGE

BNP Native Protein - NBP1-99567 from Novus Biologicals

Category Protein
Prices $275.00
Sizes 1 mg
Source Synthetic
Species Human

Recombinant human NT-proBNP Protein (OPCA00732) - OPCA00732 from Aviva Systems Biology

Category Protein
Prices $220.00
Sizes 50 µg
Species Human

Recombinant rat Natriuretic peptides B (OPCA00864) - OPCA00864 from Aviva Systems Biology

Category Protein
Prices $198.00
Sizes 50 µg
Species Rat

proBNP Protein (OPMA04591) - OPMA04591 from Aviva Systems Biology

Category Protein
Prices $670.00
Sizes 10 µg
Source E. coli

Human proBNP Protein (OPMA04592) - OPMA04592 from Aviva Systems Biology

Category Protein
Prices $605.00
Sizes 10 µg
Source E. coli
Species Human

BNP Protein (OPPA00590) - OPPA00590 from Aviva Systems Biology

Category Protein
Prices $100.00
Sizes 2 µg
Source E. Coli

BNP Protein (OPPA00631) - OPPA00631 from Aviva Systems Biology

Category Protein
Prices $540.00
Sizes 10 mg

BNP Protein (OPPA01614) - OPPA01614 from Aviva Systems Biology

Category Protein
Prices $100.00
Sizes 2 µg
Source E. Coli

SYNTHETIC Human BRAIN NATRIURETIC PEPTIDE Protein (OPSA10472) - OPSA10472 from Aviva Systems Biology

Category Protein
Prices $190.00
Sizes 100 µg
Species Human

Human BNP protein (His Tag) - orb80284 from Biorbyt

Category Protein
Prices $170.00, $289.00
Sizes 2 μg, 10 μg
Species Human

Human BNP protein - orb168942 from Biorbyt

Category Protein
Prices $170.00, $289.00
Sizes 2 μg, 10 μg
Source E. coli

Human NT-proBNP protein - orb246681 from Biorbyt

Category Protein
Prices $340.00, $629.00, $1,003.00, $1,556.00
Sizes 50 μg, 200 μg, 500 μg, 1 mg
Species Human

Human NPPB protein - orb244411 from Biorbyt

Category Protein
Prices $340.00, $629.00, $1,003.00, $1,556.00
Sizes 50 μg, 200 μg, 500 μg, 1 mg
Species Human

Human NPPB protein - orb49550 from Biorbyt

Category Protein
Prices $323.00, $485.00, $1,904.00, $2,695.00
Sizes 10 μg, 50 μg, 500 μg, 1 mg
Species Human

Human BNP protein - orb80285 from Biorbyt

Category Protein
Prices $357.00, $553.00
Sizes 10 mg, 25 mg
Species Human
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