Gene Symbol |
PXDNL
|
Entrez Gene |
137902
|
Alt Symbol |
PMR1, PRM1, VPO2
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
peroxidasin-like
|
Other Description |
cardiac peroxidase|cardiovascular peroxidase 2|peroxidasin homolog-like|peroxidasin-like protein|polysomal ribonuclease 1 homolog|vascular peroxidase 2
|
Swissprots |
B6CGZ3 A1KZ92 Q96LH9 B5ME43 H0YBM9 Q6ZMR2
|
Accessions |
A1KZ92 EAW86707 EAW86708 AI127081 AK058200 BAB71713 AK131524 BAD18663 AY877349 AAX70929 BC132813 DB337228 EU170240 ABX24517 HG501154 KJ545488 AHZ56584 XM_005251168 XP_005251225 XM_006716420 XP_006716483 XM_011517456 XP_011515758 XM_011517457 XP_011515759 XM_011517458 XP_011515760 XM_011517459 XP_011515761 XR_928757 NM_144651 NP_653252
|
Function |
Isoform PMR1: Endonuclease selectively degrading some target mRNAs while they are engaged by translating ribosomes, among which albumin and beta-globin mRNAs. {ECO:0000269|PubMed:22543864}.
|
Subcellular Location |
Secreted {ECO:0000305}.
|
Tissue Specificity |
the 57 kDa isoform PMR1 is the only form detected at protein levels in human cell lines. {ECO:0000269|PubMed:22543864}.
|