Gene Symbol | KRTAP11-1 |
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Entrez Gene | 337880 |
Alt Symbol | HACL-1, HACL1, KAP11.1 |
Species | Human |
Gene Type | protein-coding |
Description | keratin associated protein 11-1 |
Other Description | high sulfur keratin-associated protein 11.1|keratin-associated protein 11-1 |
Swissprots | Q8IUC1 A1L4I8 |
Accessions | Q8IUC1 AB096963 BAE46378 AJ457065 CAD29721 BC130555 AAI30556 BC130557 AAI30558 NM_175858 NP_787054 |
Function | In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high- sulfur and high-glycine-tyrosine keratins. |
Tissue Specificity | Expressed in the upper matrix and in the entire hair cortex. |
KRTAP11-1 CRISPR/Cas9 KO Plasmid (h) - sc-415478 from Santa Cruz Biotechnology
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KRTAP11-1 HDR Plasmid (h) - sc-415478-HDR from Santa Cruz Biotechnology
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KRTAP11-1 Double Nickase Plasmid (h) - sc-415478-NIC from Santa Cruz Biotechnology
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KRTAP11-1 Double Nickase Plasmid (h2) - sc-415478-NIC-2 from Santa Cruz Biotechnology
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KRTAP11-1 CRISPR Activation Plasmid (h) - sc-415478-ACT from Santa Cruz Biotechnology
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KRTAP11-1 CRISPR Activation Plasmid (h2) - sc-415478-ACT-2 from Santa Cruz Biotechnology
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KRTAP11-1 Lentiviral Activation Particles (h) - sc-415478-LAC from Santa Cruz Biotechnology
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KRTAP11-1 Lentiviral Activation Particles (h2) - sc-415478-LAC-2 from Santa Cruz Biotechnology
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KRTAP11-1 siRNA (h) - sc-91531 from Santa Cruz Biotechnology
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KRTAP11-1 shRNA Plasmid (h) - sc-91531-SH from Santa Cruz Biotechnology
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KRTAP11-1 shRNA (h) Lentiviral Particles - sc-91531-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN11427 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND11427 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR03753 from Sigma-Aldrich
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KRTAP11-1 siRNA (Human) - CRJ7210 from Cohesion Biosciences
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shRNA set against Human KRTAP11-1(NM_175858.2) - SHH138701 from Creative biogene
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KRTAP11-1 shRNA Plasmid (Human) - CHJ7210 from Cohesion Biosciences
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KRTAP11-1 miRNA 3'UTR clone - MiUTR1H-05486 from Creative biogene
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