Gene Symbol | IL1A |
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Entrez Gene | 100064969 |
Alt Symbol | - |
Species | Horse |
Gene Type | protein-coding |
Description | interleukin 1, alpha |
Other Description | IL-1 alpha|interleukin-1 alpha |
Swissprots | Q28385 O77743 |
Accessions | Q28385 D42146 BAA07717 U92480 AAC39255 NM_001082500 NP_001075969 |
Function | Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells (By similarity). {ECO:0000250}. |
Subcellular Location | Secreted. Note=The lack of a specific hydrophobic segment in the precursor sequence suggests that IL-1 is released by damaged cells or is secreted by a mechanism differing from that used for other secretory proteins. |
Top Pathways | MAPK signaling pathway, Apoptosis, Inflammatory bowel disease (IBD), Non-alcoholic fatty liver disease (NAFLD), Hematopoietic cell lineage |
IL1 alpha full length protein - ab128521 from Abcam
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Horse Interleukin 1 Alpha Protein - abx067382 from Abbexa
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Interleukin 1 Alpha (IL1a), Equine - 20-6193 from ARP American Research Products
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Recombinant Equine IL1A - IL1A-207E from Creative Biomart
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Recombinant Horse Interleukin-1 alpha(IL1A) - CSB-YP636720HO CSB-EP636720HO CSB-BP636720HO CSB-MP636720HO from Cusabio
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Equine IL-1 alpha Recombinant Protein - 6488 from ImmunoChemistry Technologies
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IL1A Recombinant Protein (OPCD04322) - OPCD04322 from Aviva Systems Biology
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Interleukin 1 Alpha (IL1a), Recombinant Protein - MBS2012076 from MyBioSource
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Interleukin-1 alpha (IL1A), Recombinant Protein - MBS1338360 from MyBioSource
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