Gene Symbol | AREG |
---|---|
Entrez Gene | 374 |
Alt Symbol | AR, AREGB, CRDGF, SDGF |
Species | Human |
Gene Type | protein-coding |
Description | amphiregulin |
Other Description | amphiregulin B|colorectum cell-derived growth factor|schwannoma-derived growth factor |
Swissprots | P15514 Q5U026 |
Accessions | AAA51773 AAR05438 EAX05710 P15514 AK023449 AW014754 BC009799 AAH09799 BC146953 AAI46954 BC146967 AAI46968 BT019866 AAV38669 DQ892890 ABM83816 DQ896137 ABM87136 HY047499 M30704 AAA51781 NM_001657 NP_001648 |
Function | Ligand of the EGF receptor/EGFR. Autocrine growth factor as well as a mitogen for a broad range of target cells including astrocytes, Schwann cells and fibroblasts. |
Subcellular Location | Membrane; Single-pass membrane protein. |
Top Pathways | ErbB signaling pathway, Hippo signaling pathway |