Gene Symbol |
Gpld1
|
Entrez Gene |
14756
|
Alt Symbol |
6330541J12Rik, AW546131
|
Species |
Mouse
|
Gene Type |
protein-coding
|
Description |
glycosylphosphatidylinositol specific phospholipase D1
|
Other Description |
GPI-PLD|GPI-specific phospholipase D|PI-G PLD|glycoprotein phospholipase D|glycosyl-phosphatidylinositol-specific phospholipase D|phosphatidylinositol-glycan-specific phospholipase D
|
Swissprots |
O70362
|
Accessions |
CAI26087 EDL32465 EDL32466 EDL32467 O70362 AF050666 AAC77799 AK004957 BAB23698 AK020095 AY081194 AAL87452 AY333960 AAP93132 BC019146 AAH19146 BY236833 XM_011244282 XP_011242584 NM_008156 NP_032182
|
Function |
This protein hydrolyzes the inositol phosphate linkage in proteins anchored by phosphatidylinositol glycans (GPI-anchor) thus releasing these proteins from the membrane. {ECO:0000269|PubMed:9716655}.
|
Subcellular Location |
Secreted. Note=Associated with the High- Density Lipoproteins (HDL). {ECO:0000250}.
|
Tissue Specificity |
Widely expressed. {ECO:0000269|PubMed:9716655}.
|
Top Pathways |
Glycosylphosphatidylinositol(GPI)-anchor biosynthesis
|