| Gene Symbol | PIGN |
|---|---|
| Entrez Gene | 23556 |
| Alt Symbol | MCAHS, MCAHS1, MCD4, MDC4, PIG-N |
| Species | Human |
| Gene Type | protein-coding |
| Description | phosphatidylinositol glycan anchor biosynthesis, class N |
| Other Description | GPI ethanolamine phosphate transferase 1|MCD4 homolog|phosphatidylinositol-glycan biosynthesis class N protein |
| Swissprots | Q7L8F8 O95427 Q9NT05 Q8TC01 |
| Accessions | EAW63116 EAW63117 EAW63118 EAW63119 O95427 AF109219 AAD11432 AK000730 AK315134 BAG37585 AL137607 CAB70839 BC028363 AAH28363 BF112133 BM683126 BM830623 BQ023276 BU739970 DB093302 DB239067 JF432309 ADZ15526 XM_011525889 XP_011524191 XM_011525890 XP_011524192 XM_011525891 XP_011524193 XM_011525892 XP_011524194 XM_011525893 XP_011524195 XM_011525894 XP_011524196 XM_011525895 XP_011524197 XM_011525896 XP_011524198 XM_011525897 XP_011524199 XM_011525898 XP_011524200 NM_012327 NP_036459 NM_176787 NP_789744 |
| Function | Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the first alpha-1,4-linked mannose of the glycosylphosphatidylinositol precursor of GPI-anchor (By similarity). May act as suppressor of replication stress and chromosome missegregation. {ECO:0000250, ECO:0000269|PubMed:23446422}. |
| Subcellular Location | Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. |
| Top Pathways | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis |