Gene Symbol | PIGN |
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Entrez Gene | 23556 |
Alt Symbol | MCAHS, MCAHS1, MCD4, MDC4, PIG-N |
Species | Human |
Gene Type | protein-coding |
Description | phosphatidylinositol glycan anchor biosynthesis, class N |
Other Description | GPI ethanolamine phosphate transferase 1|MCD4 homolog|phosphatidylinositol-glycan biosynthesis class N protein |
Swissprots | Q7L8F8 O95427 Q9NT05 Q8TC01 |
Accessions | EAW63116 EAW63117 EAW63118 EAW63119 O95427 AF109219 AAD11432 AK000730 AK315134 BAG37585 AL137607 CAB70839 BC028363 AAH28363 BF112133 BM683126 BM830623 BQ023276 BU739970 DB093302 DB239067 JF432309 ADZ15526 XM_011525889 XP_011524191 XM_011525890 XP_011524192 XM_011525891 XP_011524193 XM_011525892 XP_011524194 XM_011525893 XP_011524195 XM_011525894 XP_011524196 XM_011525895 XP_011524197 XM_011525896 XP_011524198 XM_011525897 XP_011524199 XM_011525898 XP_011524200 NM_012327 NP_036459 NM_176787 NP_789744 |
Function | Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the first alpha-1,4-linked mannose of the glycosylphosphatidylinositol precursor of GPI-anchor (By similarity). May act as suppressor of replication stress and chromosome missegregation. {ECO:0000250, ECO:0000269|PubMed:23446422}. |
Subcellular Location | Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. |
Top Pathways | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis |
PIG-N (L-20) - sc-85103 from Santa Cruz Biotechnology
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PIG-N (N-20) - sc-85104 from Santa Cruz Biotechnology
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Anti-PIGN antibody - ab103190 from Abcam
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Anti-PIGN Antibody (aa206-235, AP) - LS-C266333 from LifeSpan Bioscience
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Anti-PIGN Antibody (aa206-235, Biotin) - LS-C266335 from LifeSpan Bioscience
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Anti-PIGN Antibody (aa206-235, FITC) - LS-C266336 from LifeSpan Bioscience
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Anti-PIGN Antibody (aa206-235, APC) - LS-C266334 from LifeSpan Bioscience
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Anti-PIGN Antibody (aa206-235, PE) - LS-C266338 from LifeSpan Bioscience
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Anti-PIGN Antibody (aa206-235, Azide-free, HRP) - LS-C266337 from LifeSpan Bioscience
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Anti-PIGN Antibody (aa213-243) - LS-C324031 from LifeSpan Bioscience
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Anti-PIGN Antibody (aa206-235) - LS-C163716 from LifeSpan Bioscience
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PIGN Antibody - NBP1-81249 from Novus Biologicals
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PIGN Antibody - NBP1-81248 from Novus Biologicals
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Anti-PIGN antibody produced in rabbit - HPA040374 from Sigma-Aldrich
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Anti-PIGN antibody produced in rabbit - HPA039922 from Sigma-Aldrich
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PIGN-Antibody-N-term - AP9751a from Abgent, a WuXi AppTec company
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PIGN Antibody - N-terminal region (OAAB06351) - OAAB06351 from Aviva Systems Biology
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PIGN (N-term) antibody - AP53298PU-N from Acris Antibodies
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PIGN antibody - 14004-1-AP from Proteintech Group
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Anti-PIGN monoclonal antibody - DCABH-12918 from Creative Diagnostics
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PIGN Polyclonal Antibody - PA5-26755 from Thermo Fisher Scientific
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PIGN, Polyclonal Antibody - MBS9208094 from MyBioSource
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PIGN antibody - orb40454 from Biorbyt
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Anti-PIGN polyclonal antibody - CABT-BL5402 from Creative Diagnostics
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PIGN Antibody - 64-094 from ProSci
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