Gene Symbol |
BDNF
|
Entrez Gene |
403461
|
Alt Symbol |
-
|
Species |
Dog
|
Gene Type |
protein-coding
|
Description |
brain-derived neurotrophic factor
|
Other Description |
-
|
Swissprots |
Q7YRB4 Q9BFH2
|
Accessions |
AAG47532 Q7YRB4 AB105074 BAC81435 XM_005633263 XP_005633320 XM_005633264 XP_005633321 XM_005633265 XP_005633322 XM_005633266 XP_005633323 NM_001002975 NP_001002975
|
Function |
During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS (By similarity). {ECO:0000250}.
|
Subcellular Location |
Secreted.
|
Top Pathways |
Huntington's disease, MAPK signaling pathway, Neurotrophin signaling pathway, Cocaine addiction, Alcoholism
|