Gene Symbol |
CYP26A1
|
Entrez Gene |
408183
|
Alt Symbol |
CYP26A
|
Species |
Chicken
|
Gene Type |
protein-coding
|
Description |
cytochrome P450, family 26, subfamily A, polypeptide 1
|
Other Description |
cytochrome P450 26A1|retinoic acid-degrading enzyme CYP26
|
Swissprots |
Q9PUG2 Q9PUB4
|
Accessions |
Q9PUB4 AF185266 AAD56546 AF199462 AAF09250 NM_001001129 NP_001001129
|
Function |
Plays a key role in retinoic acid metabolism. Appears to be involved in the specific inactivation of all-trans-retinoic acid (RA). Responsible for generation of several hydroxylated forms of RA, including 4-OH-RA, 4-oxo-RA, and 18-OH-RA.
|
Subcellular Location |
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
|
Top Pathways |
Retinol metabolism
|