Gene Symbol | CTSZ |
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Entrez Gene | 1522 |
Alt Symbol | CTSX |
Species | Human |
Gene Type | protein-coding |
Description | cathepsin Z |
Other Description | carboxypeptidase LB|cathepsin B2|cathepsin IV|cathepsin P|cathepsin X|cathepsin Y|cathepsin Z1|cysteine-type carboxypeptidase|lysosomal carboxypeptidase B|preprocathepsin P |
Swissprots | Q9UQV6 B2RC40 Q9UBR2 Q9UQV5 O75331 |
Accessions | AAF13148 EAW75448 EAW75449 EAW75450 Q9UBR2 AF009923 AAC63141 AF073890 AAC61477 AF136273 AAF13145 AK310046 AK314931 BAG37437 AM392668 CAL37546 BC025419 BC042168 AAH42168 BT019915 AAV38718 NM_001336 NP_001327 |
Function | Exhibits carboxy-monopeptidase as well as carboxy- dipeptidase activity. |
Subcellular Location | Lysosome. |
Tissue Specificity | Widely expressed. {ECO:0000269|PubMed:10653163}. |
Top Pathways | Lysosome |
cathepsin Z CRISPR/Cas9 KO Plasmid (h) - sc-403244 from Santa Cruz Biotechnology
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cathepsin Z HDR Plasmid (h) - sc-403244-HDR from Santa Cruz Biotechnology
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cathepsin Z Double Nickase Plasmid (h) - sc-403244-NIC from Santa Cruz Biotechnology
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cathepsin Z Double Nickase Plasmid (h2) - sc-403244-NIC-2 from Santa Cruz Biotechnology
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cathepsin Z CRISPR Activation Plasmid (h) - sc-403244-ACT from Santa Cruz Biotechnology
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cathepsin Z CRISPR Activation Plasmid (h2) - sc-403244-ACT-2 from Santa Cruz Biotechnology
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cathepsin Z Lentiviral Activation Particles (h) - sc-403244-LAC from Santa Cruz Biotechnology
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cathepsin Z Lentiviral Activation Particles (h2) - sc-403244-LAC-2 from Santa Cruz Biotechnology
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cathepsin Z siRNA (h) - sc-44661 from Santa Cruz Biotechnology
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cathepsin Z shRNA Plasmid (h) - sc-44661-SH from Santa Cruz Biotechnology
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cathepsin Z shRNA (h) Lentiviral Particles - sc-44661-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU131221 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN1981 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1981 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR04013 from Sigma-Aldrich
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CTSZ siRNA (Human) - CRH1076 from Cohesion Biosciences
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CTSZ - MBS8225230 from MyBioSource
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cathepsin Z CRISPR/Cas9 KO Plasmid (h2) - sc-403244-KO-2 from Santa Cruz Biotechnology
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cathepsin Z HDR Plasmid (h2) - sc-403244-HDR-2 from Santa Cruz Biotechnology
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shRNA set against Human CTSZ (NM_001336.3) - SHH271685 from Creative biogene
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Human CTSZ siRNA - orb261578 from Biorbyt
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CTSZ shRNA Plasmid (Human) - CHH1076 from Cohesion Biosciences
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CTSZ miRNA 3'UTR clone - MiUTR3H-05736 from Creative biogene
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