| Gene Symbol |
ATP12A
|
| Entrez Gene |
479
|
| Alt Symbol |
ATP1AL1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
ATPase, H+/K+ transporting, nongastric, alpha polypeptide
|
| Other Description |
ATPase, Na+/K+ transporting, alpha polypeptide-like 1|non-gastric H(+)/K(+) ATPase alpha subunit|non-gastric H(+)/K(+) ATPase subunit alpha|potassium-transporting ATPase alpha chain 2|proton pump
|
| Swissprots |
P54707 Q13816 Q8N5U2 Q5W035 Q16734 Q13817
|
| Accessions |
AAA35576 AAC37589 CAA49477 CAA49478 EAX08343 EAX08344 EAX08345 EAX08346 P54707 AK292968 BAF85657 AK303498 BAG64531 BC031609 AAH31609 CA450333 DB216724 DB232979 JF432299 ADZ15516 M16797 AAA51802 U02076 AAB37755 NM_001185085 NP_001172014 NM_001676 NP_001667
|
| Function |
Catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. Responsible for potassium absorption in various tissues.
|
| Subcellular Location |
Membrane; Multi-pass membrane protein.
|
| Tissue Specificity |
Found in skin and kidney. Detected in prostate basal cells (at protein level). Expression is increased in benign prostate hyperplasia and tumor tissues (at protein level). {ECO:0000269|PubMed:22179016, ECO:0000269|PubMed:9872395}.
|
| Top Pathways |
Oxidative phosphorylation
|
![Western Blot: ATP12A Overexpression Lysate (Adult Normal) [NBL1-07806] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for ATP12A.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/1065_ATP12A%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-07806-img0002.jpg)