Gene Symbol | MOCS1 |
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Entrez Gene | 4337 |
Alt Symbol | MIG11, MOCOD, MOCODA |
Species | Human |
Gene Type | protein-coding |
Description | molybdenum cofactor synthesis 1 |
Other Description | MOCS1A enzyme|cell migration-inducing gene 11 protein|migration-inducing gene 11 protein|molybdenum cofactor biosynthesis protein 1|molybdenum cofactor biosynthesis protein A|molybdenum cofactor synthesis-step 1 protein A-B |
Swissprots | Q5TCE1 Q5TCF0 Q5TCE6 O75710 Q9NZB7 B4DTP1 B3KPT7 Q9NZB8 Q9UEM1 O14941 Q5TCF1 Q5TCE2 Q8N418 Q5TCE9 O14940 Q5J7W0 |
Accessions | CAC44526 CAC44527 CAI20007 CAI20008 CAI20009 CAI20011 CAI20012 CAI20013 CAI20014 CAI20015 EAX03998 EAX03999 EAX04000 EAX04001 EAX04002 Q9NZB8 AF034374 AAB87523 AF214015 AAF67843 AF214022 AAF67857 AF214023 AAF67858 AI122656 AJ224328 CAA11897 AK056740 BAG51799 AK091306 AK300300 BAG62053 AV724791 AY423726 AAS00489 BC036839 AAH36839 BC140421 AAI40422 CA944911 CN267723 CX787499 DC377054 DC410181 XM_011514632 XP_011512934 XM_011514633 XP_011512935 XM_011514634 XP_011512936 XM_011514635 XP_011512937 XR_926225 NM_001075098 NP_001068566 NM_005943 NP_005934 NR_033233 NM_005942 NM_138928 |
Function | Isoform MOCS1A and isoform MOCS1B probably form a complex that catalyzes the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z). {ECO:0000269|PubMed:11891227}. |
Tissue Specificity | Isoform MOCS1A and isoform 2 are widely expressed. {ECO:0000269|PubMed:12208140, ECO:0000269|PubMed:9731530}. |
Top Pathways | Sulfur relay system, Folate biosynthesis |
MOCS1 CRISPR/Cas9 KO Plasmid (h) - sc-405774 from Santa Cruz Biotechnology
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MOCS1 HDR Plasmid (h) - sc-405774-HDR from Santa Cruz Biotechnology
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MOCS1 Double Nickase Plasmid (h) - sc-405774-NIC from Santa Cruz Biotechnology
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MOCS1 Double Nickase Plasmid (h2) - sc-405774-NIC-2 from Santa Cruz Biotechnology
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MOCS1 CRISPR Activation Plasmid (h) - sc-405774-ACT from Santa Cruz Biotechnology
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MOCS1 CRISPR Activation Plasmid (h2) - sc-405774-ACT-2 from Santa Cruz Biotechnology
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MOCS1 Lentiviral Activation Particles (h) - sc-405774-LAC from Santa Cruz Biotechnology
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MOCS1 Lentiviral Activation Particles (h2) - sc-405774-LAC-2 from Santa Cruz Biotechnology
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MOCS1 siRNA (h) - sc-95639 from Santa Cruz Biotechnology
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MOCS1 shRNA Plasmid (h) - sc-95639-SH from Santa Cruz Biotechnology
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MOCS1 shRNA (h) Lentiviral Particles - sc-95639-V from Santa Cruz Biotechnology
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MOCS1 RNAi - H00004337-R01 from Novus Biologicals
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MOCS1 RNAi - H00004337-R03 from Novus Biologicals
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MISSION® esiRNA - EHU115811 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN14459 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND14459 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR10156 from Sigma-Aldrich
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MOCS1 siRNA (Human) - CRH2946 from Cohesion Biosciences
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MOCS1 RNAi - H00004337-R02 from Novus Biologicals
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shRNA set against Human MOCS1 (NM_005943.5) - SHH343368 from Creative biogene
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Human MOCS1 siRNA - orb263448 from Biorbyt
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MOCS1 shRNA Plasmid (Human) - CHH2946 from Cohesion Biosciences
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MOCS1 miRNA 3'UTR clone - MiUTR4H-TG05572 from Creative biogene
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