GALNT9
| Gene Symbol | GALNT9 |
|---|---|
| Entrez Gene | 50614 |
| Alt Symbol | GALNAC-T9, GALNACT9 |
| Species | Human |
| Gene Type | protein-coding |
| Description | polypeptide N-acetylgalactosaminyltransferase 9 |
| Other Description | GalNAc transferase 9|UDP-GalNAc: polypeptide N-acetylgalactosaminyltransferase 9|UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 9|UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 9 (GalNAc-T9)|polypeptide GalNAc transferase 9|pp-GaNTase 9|protein-UDP acetylgalactosaminyltransferase 9 |
| Swissprots | Q8NFR1 Q6NT54 Q52LR8 Q9HCQ5 |
| Accessions | Q9HCQ5 AB040672 BAB13699 AF458594 AAM49722 AJ505960 CAD44540 AK054820 BAG51429 AK055773 BAG51570 BC069354 BC093817 AAH93817 BC093819 AAH93819 BC157845 AAI57846 BC171844 AAI71844 BI760629 BM672467 BM925654 CB154648 DA206384 DA370980 DR001000 HQ258120 ADR82874 NM_001122636 NP_001116108 NM_021808 NP_068580 |
| Function | Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D- galactosamine residue to a serine or threonine residue on the protein receptor. Does not glycosylate apomucin or SDC3. |
| Subcellular Location | Golgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}. |
| Tissue Specificity | Specifically expressed in brain. Not expressed in heart, placenta, lung, liver, skeletal muscle, kidney, pancreas, spleen, thymus, prostate, testis, ovary, small intestine, colon and leukocyte. In brain, it is expressed in cerebellum, frontal lobe, temporal lobe, putamen and spinal cord, weakly expressed in cerebral cortex. Not expressed in medulla and occipital pole. {ECO:0000269|PubMed:10978536}. |
| Top Pathways | Mucin type O-Glycan biosynthesis |
GalNAc-T9 CRISPR/Cas9 KO Plasmid (h) - sc-412077 from Santa Cruz Biotechnology
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GalNAc-T9 HDR Plasmid (h) - sc-412077-HDR from Santa Cruz Biotechnology
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GalNAc-T9 Double Nickase Plasmid (h) - sc-412077-NIC from Santa Cruz Biotechnology
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GalNAc-T9 Double Nickase Plasmid (h2) - sc-412077-NIC-2 from Santa Cruz Biotechnology
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GalNAc-T9 CRISPR Activation Plasmid (h) - sc-412077-ACT from Santa Cruz Biotechnology
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GalNAc-T9 CRISPR Activation Plasmid (h2) - sc-412077-ACT-2 from Santa Cruz Biotechnology
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GalNAc-T9 Lentiviral Activation Particles (h) - sc-412077-LAC from Santa Cruz Biotechnology
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GalNAc-T9 Lentiviral Activation Particles (h2) - sc-412077-LAC-2 from Santa Cruz Biotechnology
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GalNAc-T9 siRNA (h) - sc-75104 from Santa Cruz Biotechnology
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GalNAc-T9 shRNA Plasmid (h) - sc-75104-SH from Santa Cruz Biotechnology
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GalNAc-T9 shRNA (h) Lentiviral Particles - sc-75104-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU014421 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN9114 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9114 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR06166 from Sigma-Aldrich
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GALNT9 siRNA (Human) - CRH9386 from Cohesion Biosciences
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GALNT9 RNAi - H00050614-R01 from Novus Biologicals
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GALNT9 - MBS8235607 from MyBioSource
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shRNA set against Human GALNT9 (NM_021808.3) - SHH299101 from Creative biogene
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GALNT9 shRNA Plasmid (Human) - CHH9386 from Cohesion Biosciences
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GALNT9 miRNA 3'UTR clone - MiUTR3H-08312 from Creative biogene
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GALNT9 miRNA 3'UTR clone - MiUTR3H-08313 from Creative biogene
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