| Gene Symbol |
C8B
|
| Entrez Gene |
732
|
| Alt Symbol |
C82
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
complement component 8, beta polypeptide
|
| Other Description |
complement component 8 subunit beta|complement component C8 beta chain
|
| Swissprots |
A1L4K7 P07358
|
| Accessions |
EAX06641 EAX06642 EAX06643 P07358 AK292740 BAF85429 AK298425 BAH12786 AK298444 BAH12791 AK313382 BAG36180 AK316209 BAH14580 BC020701 AAH20701 BC130575 AAI30576 CD364465 HQ258464 ADR83218 M16973 AAA51862 X04393 CAA27981 NM_000066 NP_000057 NM_001278543 NP_001265472 NM_001278544 NP_001265473
|
| Function |
Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells.
|
| Subcellular Location |
Secreted.
|
| Top Pathways |
Complement and coagulation cascades, Systemic lupus erythematosus, Prion diseases, Amoebiasis
|
