Gene Symbol | PPP2R3B |
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Entrez Gene | 28227 |
Alt Symbol | NYREN8, PPP2R3L, PPP2R3LY, PR48 |
Species | Human |
Gene Type | protein-coding |
Description | protein phosphatase 2, regulatory subunit B'', beta |
Other Description | NY-REN-8 antigen|PP2A, subunit B, PR48 isoform|protein phosphatase 2 (formerly 2A), regulatory subunit B'', beta|serine/threonine protein phosphatase 2A, 48kDa regulatory subunit B|serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta |
Swissprots | Q9Y5P8 Q6P4G9 Q96H01 Q7RTT1 |
Accessions | EAW66818 EAW66819 Q9Y5P8 AB209137 BAD92374 AF135016 AAD38515 AF155098 AAD42864 AI248426 AK293506 BAG56990 AL157501 CAB75680 BC009032 AAH09032 BC011180 AAH11180 BC063429 AAH63429 BF530463 BI828434 BK000521 DAA00385 BM666129 BM676246 BM715684 BU845905 CB218994 DA061573 HQ447089 ADQ31576 XM_011545630 XP_011543932 XM_011546177 XP_011544479 NM_013239 NP_037371 NM_199326 |
Function | The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:10629059}. |
Top Pathways | mRNA surveillance pathway, Dopaminergic synapse, PI3K-Akt signaling pathway, Adrenergic signaling in cardiomyocytes, AMPK signaling pathway |
PR48 siRNA (h) - sc-39204 from Santa Cruz Biotechnology
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PR48 shRNA Plasmid (h) - sc-39204-SH from Santa Cruz Biotechnology
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PR48 shRNA (h) Lentiviral Particles - sc-39204-V from Santa Cruz Biotechnology
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PR48 RNAi - H00028227-R04 from Novus Biologicals
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MISSION® esiRNA - EHU074491 from Sigma-Aldrich
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MISSION® Human Phosphatase - SIHP0629 from Sigma-Aldrich
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MISSION® Human Phosphatase - SIHP0628 from Sigma-Aldrich
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MISSION® Human Phosphatase - SIHP0630 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN17296 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17296 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR00187 from Sigma-Aldrich
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PPP2R3B siRNA (Human) - CRH9112 from Cohesion Biosciences
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PR48 RNAi - H00028227-R03 from Novus Biologicals
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shRNA set against Human PPP2R3B (NM_013239.4) - SHH381444 from Creative biogene
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PPP2R3B shRNA Plasmid (Human) - CHH9112 from Cohesion Biosciences
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PPP2R3B miRNA 3'UTR clone - MiUTR3H-02698 from Creative biogene
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