Gene Symbol | KRTAP1-5 |
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Entrez Gene | 83895 |
Alt Symbol | KAP1.5, KRTAP1.5 |
Species | Human |
Gene Type | protein-coding |
Description | keratin associated protein 1-5 |
Other Description | high sulfur keratin-associated protein 1.5|keratin associated protein 1.5|keratin-associated protein 1-5|keratin-associated protein 1.5 |
Swissprots | A6NJW6 A6NLZ6 Q52LP6 Q9BYS1 B6ZDR1 |
Accessions | EAW60697 Q9BYS1 AJ406928 CAC27567 BC069533 AAH69533 BC093841 AAH93841 BC101555 AAI01556 NM_031957 NP_114163 |
Function | In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high- sulfur and high-glycine-tyrosine keratins. |
Tissue Specificity | Expressed in the middle/upper portions of the hair cortex, in the region termed the keratogenous zone. {ECO:0000269|PubMed:11279113}. |
KRTAP1-5 CRISPR/Cas9 KO Plasmid (h) - sc-418329 from Santa Cruz Biotechnology
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KRTAP1-5 HDR Plasmid (h) - sc-418329-HDR from Santa Cruz Biotechnology
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KRTAP1-5 Double Nickase Plasmid (h) - sc-418329-NIC from Santa Cruz Biotechnology
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KRTAP1-5 Double Nickase Plasmid (h2) - sc-418329-NIC-2 from Santa Cruz Biotechnology
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KRTAP1-5 CRISPR Activation Plasmid (h) - sc-418329-ACT from Santa Cruz Biotechnology
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KRTAP1-5 CRISPR Activation Plasmid (h2) - sc-418329-ACT-2 from Santa Cruz Biotechnology
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KRTAP1-5 Lentiviral Activation Particles (h) - sc-418329-LAC from Santa Cruz Biotechnology
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KRTAP1-5 Lentiviral Activation Particles (h2) - sc-418329-LAC-2 from Santa Cruz Biotechnology
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KRTAP1-5 siRNA (h) - sc-94154 from Santa Cruz Biotechnology
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KRTAP1-5 shRNA Plasmid (h) - sc-94154-SH from Santa Cruz Biotechnology
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KRTAP1-5 shRNA (h) Lentiviral Particles - sc-94154-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU224411 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN11437 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND11437 from Sigma-Aldrich
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KRTAP1-5 siRNA (Human) - CRJ3232 from Cohesion Biosciences
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shRNA set against Human KRTAP1-5(NM_031957.1) - SHH138971 from Creative biogene
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Human KRTAP1-5 siRNA - orb273733 from Biorbyt
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KRTAP1-5 shRNA Plasmid (Human) - CHJ3232 from Cohesion Biosciences
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KRTAP1-5 miRNA 3'UTR clone - MiUTR1H-05496 from Creative biogene
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