| Gene Symbol | phl |
|---|---|
| Entrez Gene | 31221 |
| Alt Symbol | 11-29, C110, CG2845, D-RAF, D-Raf, D-raf, D-raf1, DRaf, DRaf1, Dmel\CG2845, Draf, Draf-1, Draf1, EG:BACH48C10.3, Phl, RAF, Raf, Raf/phl, Raf1, draf, l(1)2Fe, l(1)G0475, l(1)ph, l(1)phl, l(1)pole hole, l(1)polehole, l(1)polehole/draf, l(1)raf, lincRNA.937, |
| Species | Drosophila |
| Gene Type | protein-coding |
| Description | pole hole |
| Other Description | CG2845-PA|CG2845-PE|Raf|l(1)pole hole|phl-PA|phl-PE|pole-hole|polehole|raf-like-oncogene-1 |
| Swissprots | Q8I0D9 Q0KHW7 Q9W4Z3 Q8ISE1 P11346 A8JUV5 Q9NEH9 Q8I086 Q8ISE2 Q8ISE3 |
| Accessions | AAF45774 ABW09328 P11346 AY089490 AAL90228 NM_001103397 NP_001096867 NM_080308 NP_525047 |
| Function | Serine/threonine kinase required in the early embryo for the formation of terminal structure. Also required during the proliferation of imaginal cells. May act downstream of ras1 in the sev signal transduction pathway. {ECO:0000269|PubMed:3135183, ECO:0000269|PubMed:8423783}. |
| Top Pathways | Dorso-ventral axis formation, MAPK signaling pathway - fly |
D-Raf1 (dH-19) - sc-15745 from Santa Cruz Biotechnology
|